"Endothelin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
| Descriptor ID |
D019332
|
| MeSH Number(s) |
D12.644.276.400.225 D12.776.467.400.225 D23.529.400.225
|
| Concept/Terms |
Proendothelin (1-38)- Proendothelin (1-38)
- Big Endothelin
- Big Endothelin-1
- Big Endothelin 1
- Endothelin-1, Big
- Endothelin, Big
Preproendothelin-1- Preproendothelin-1
- Preproendothelin 1
- Preproendothelin
- Proendothelin-1 Precursor
- Precursor, Proendothelin-1
- Proendothelin 1 Precursor
|
Below are MeSH descriptors whose meaning is more general than "Endothelin-1".
Below are MeSH descriptors whose meaning is more specific than "Endothelin-1".
This graph shows the total number of publications written about "Endothelin-1" by people in this website by year, and whether "Endothelin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 1 | 2 |
| 2000 | 6 | 1 | 7 |
| 2001 | 3 | 2 | 5 |
| 2002 | 2 | 1 | 3 |
| 2003 | 4 | 4 | 8 |
| 2004 | 3 | 2 | 5 |
| 2005 | 3 | 2 | 5 |
| 2006 | 4 | 1 | 5 |
| 2007 | 2 | 1 | 3 |
| 2008 | 5 | 3 | 8 |
| 2009 | 3 | 0 | 3 |
| 2010 | 4 | 1 | 5 |
| 2011 | 5 | 1 | 6 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 0 | 1 |
| 2014 | 3 | 1 | 4 |
| 2015 | 2 | 2 | 4 |
| 2016 | 3 | 0 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 3 | 0 | 3 |
| 2022 | 0 | 3 | 3 |
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Below are the most recent publications written about "Endothelin-1" by people in Profiles.
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Endothelin A receptors contribute to senescence of brain microvascular endothelial cells. Can J Physiol Pharmacol. 2022 Dec 01; 100(12):1087-1096.
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Characterization of focal adhesion proteins in rodent hepatic stellate cells. Histochem Cell Biol. 2022 Oct; 158(4):325-334.
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Porphyromonas gingivalis infection upregulates the endothelin (ET) system in brain microvascular endothelial cells. Can J Physiol Pharmacol. 2022 Jul 01; 100(7):679-688.
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Diabetes-related sex differences in the brain endothelin system following ischemia in vivo and in human brain endothelial cells in vitro. Can J Physiol Pharmacol. 2020 Sep; 98(9):587-595.
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Endothelin-1 (ET-1) promotes a proinflammatory microglia phenotype in diabetic conditions. Can J Physiol Pharmacol. 2020 Sep; 98(9):596-603.
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Endothelin-1 and conflicting Risk Association: A new lens A Response to Leary et al, "Endothelin-1, cardiac morphology, and heart failure: the MESA angiogenesis study." J Heart Lung Transplant. 2020 08; 39(8):846.
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Endothelin-1, cardiac morphology, and heart failure: the MESA angiogenesis study. J Heart Lung Transplant. 2020 01; 39(1):45-52.
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Endothelin-1 inhibition improves the mBDNF/proBDNF ratio in endothelial cells and HT22 neurons under high glucose/palmitate growth conditions. Physiol Res. 2018 06 27; 67(Suppl 1):S237-S246.
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Caveolin 1 and G-Protein-Coupled Receptor Kinase-2 Coregulate Endothelial Nitric Oxide Synthase Activity in Sinusoidal Endothelial Cells. Am J Pathol. 2017 Apr; 187(4):896-907.
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Diabetes-mediated middle cerebral artery remodeling is restored by linagliptin: Interaction with the vascular smooth muscle cell endothelin system. Life Sci. 2016 Aug 15; 159:76-82.