"Immunoglobulin Idiotypes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
| Descriptor ID |
D007130
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| MeSH Number(s) |
D12.644.541.500.745 D12.776.124.486.485.680.745 D12.776.124.790.651.680.745 D12.776.377.715.548.680.745 D23.050.550.750 G02.111.570.060.425.580 G12.500.450
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| Concept/Terms |
Immunoglobulin Idiotypes- Immunoglobulin Idiotypes
- Idiotype, Immunoglobulin
- Immunoglobulin Idiotype
- Idiotypes, Immunoglobulin
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Idiotypes".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Idiotypes".
This graph shows the total number of publications written about "Immunoglobulin Idiotypes" by people in this website by year, and whether "Immunoglobulin Idiotypes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin Idiotypes" by people in Profiles.
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Idiotype usage by polyclonally activated B cells in experimental autoimmunity and infection. Clin Exp Immunol. 1999 Feb; 115(2):275-80.
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Genetics of immunoglobulins. Immunol Ser. 1993; 58:103-16.
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Anti-DNA idiotype network: therapeutic considerations. Lupus. 1992 Oct; 1(5):339-40.
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Human and murine anti-DNA antibodies induce the production of anti-idiotypic antibodies with autoantigen-binding properties (epibodies) through immune-network interactions. J Immunol. 1990 Dec 15; 145(12):4229-37.
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Angiotensin II (AII)-related idiotypic network. III. Comparative analysis of idiotopes and paratopes borne by monoclonal antibodies raised against AII (AB1) and its internal image (AB3). J Immunol. 1990 Sep 01; 145(5):1440-9.
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Cross-reactivity distinguishes serum and nephritogenic anti-DNA antibodies in human lupus from their natural counterparts in normal serum. J Autoimmun. 1990 Apr; 3(2):215-35.
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Genetics of immunoglobulins. Immunol Ser. 1990; 50:107-21.
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T cell up-regulation of B cells via their idiotypes contributing to the development of systemic lupus erythematosus. A hypothesis. Am J Med. 1988 Dec 23; 85(6A):32-4.
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Angiotensin II (AII)-related idiotypic network. II. Heterogeneity and fine specificity of AII internal images analyzed with monoclonal antibodies. J Immunol. 1988 May 01; 140(9):3059-65.
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Lupus serum and normal human serum contain anti-DNA antibodies with the same idiotypic marker. J Immunol. 1986 Oct 15; 137(8):2535-40.