"Antigenic Variation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Change in the surface ANTIGEN of a microorganism. There are two different types. One is a phenomenon, especially associated with INFLUENZA VIRUSES, where they undergo spontaneous variation both as slow antigenic drift and sudden emergence of new strains (antigenic shift). The second type is when certain PARASITES, especially trypanosomes, PLASMODIUM, and BORRELIA, survive the immune response of the host by changing the surface coat (antigen switching). (From Herbert et al., The Dictionary of Immunology, 4th ed)
Descriptor ID |
D000940
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MeSH Number(s) |
G05.365.073 G12.500.249
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Concept/Terms |
Antigenic Variation- Antigenic Variation
- Antigenic Variability
- Variability, Antigenic
- Variation, Antigenic
- Antigen Variation
- Variation, Antigen
Antigen Switching- Antigen Switching
- Switching, Antigen
- Switching, Antigenic
- Antigenic Switching
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Below are MeSH descriptors whose meaning is more general than "Antigenic Variation".
Below are MeSH descriptors whose meaning is more specific than "Antigenic Variation".
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Below are the most recent publications written about "Antigenic Variation" by people in Profiles.
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Immunoglobulin genes. Baillieres Clin Rheumatol. 1988 Dec; 2(3):577-83.