"Granulosa Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).
| Descriptor ID |
D006107
|
| MeSH Number(s) |
A05.360.319.114.630.535.200 A06.407.312.497.535.300 A11.382.812 A11.436.329
|
| Concept/Terms |
Granulosa Cells- Granulosa Cells
- Cell, Granulosa
- Cells, Granulosa
- Granulosa Cell
|
Below are MeSH descriptors whose meaning is more general than "Granulosa Cells".
Below are MeSH descriptors whose meaning is more specific than "Granulosa Cells".
This graph shows the total number of publications written about "Granulosa Cells" by people in this website by year, and whether "Granulosa Cells" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 3 | 0 | 3 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Granulosa Cells" by people in Profiles.
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Kordus RJ, Hossain A, Malter HE, LaVoie HA. Mitochondrial metabolic substrate utilization in granulosa cells reflects body mass index and total follicle stimulating hormone dosage in in vitro fertilization patients. J Assist Reprod Genet. 2020 Nov; 37(11):2743-2756.
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LaVoie HA. Transcriptional control of genes mediating ovarian follicular growth, differentiation, and steroidogenesis in pigs. Mol Reprod Dev. 2017 Sep; 84(9):788-801.
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Kordus RJ, LaVoie HA. Granulosa cell biomarkers to predict pregnancy in ART: pieces to solve the puzzle. Reproduction. 2017 02; 153(2):R69-R83.
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LaVoie HA, Whitfield NE, Shi B, King SR, Bose HS, Hui YY. STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis. Exp Biol Med (Maywood). 2014 Apr; 239(4):430-5.
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King SR, LaVoie HA. Gonadal transactivation of STARD1, CYP11A1 and HSD3B. Front Biosci (Landmark Ed). 2012 01 01; 17(3):824-46.
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Kumar A, Kalra B, Patel A, McDavid L, Roudebush WE. Development of a second generation anti-Müllerian hormone (AMH) ELISA. J Immunol Methods. 2010 Oct 31; 362(1-2):51-9.
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LaVoie HA, Kordus RJ, Nguyen JB, Barth JL, Hui YY. GATA depletion impacts insulin-like growth factor 1 mRNA and protein levels in luteinizing porcine granulosa cells. Biol Reprod. 2010 Dec; 83(6):1015-26.
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Hui YY, Lavoie HA. GATA4 reduction enhances 3',5'-cyclic adenosine 5'-monophosphate-stimulated steroidogenic acute regulatory protein messenger ribonucleic acid and progesterone production in luteinized porcine granulosa cells. Endocrinology. 2008 Nov; 149(11):5557-67.
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Gillio-Meina C, Hui YY, LaVoie HA. Expression of CCAAT/enhancer binding proteins alpha and beta in the porcine ovary and regulation in primary cultures of granulosa cells. Biol Reprod. 2005 May; 72(5):1194-204.
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Rusovici R, Hui YY, Lavoie HA. Epidermal growth factor-mediated inhibition of follicle-stimulating hormone-stimulated StAR gene expression in porcine granulosa cells is associated with reduced histone H3 acetylation. Biol Reprod. 2005 Apr; 72(4):862-71.