"A549 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. The cell line is positive for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION.
| Descriptor ID |
D000072283
|
| MeSH Number(s) |
A11.251.210.190.080 A11.251.860.180.080 A11.436.054
|
| Concept/Terms |
A549 Cells- A549 Cells
- A549 Cell
- Cell, A549
- Cells, A549
- A549 Cell Line
- A549 Cell Lines
- Cell Line, A549
- Cell Lines, A549
|
Below are MeSH descriptors whose meaning is more general than "A549 Cells".
Below are MeSH descriptors whose meaning is more specific than "A549 Cells".
This graph shows the total number of publications written about "A549 Cells" by people in this website by year, and whether "A549 Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 4 | 4 |
| 2017 | 0 | 3 | 3 |
| 2018 | 0 | 4 | 4 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 3 | 3 |
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Below are the most recent publications written about "A549 Cells" by people in Profiles.
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Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue. Respir Res. 2021 Oct 28; 22(1):278.
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TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nat Commun. 2021 09 09; 12(1):5337.
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Persistent effects of pair bonding in lung cancer cell growth in monogamous Peromyscus californicus. Elife. 2021 05 07; 10.
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Neuropilin-2b facilitates resistance to tyrosine kinase inhibitors in non-small cell lung cancer. J Thorac Cardiovasc Surg. 2021 08; 162(2):463-473.
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Genetic and pharmacological inhibition of acid ceramidase prevents asymmetric cell division by neosis. J Lipid Res. 2019 07; 60(7):1225-1235.
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The NMR-based characterization of the FTY720-SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET-PP2A interaction. FASEB J. 2019 06; 33(6):7647-7666.
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Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis. J Biol Chem. 2019 01 11; 294(2):502-519.
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C16-ceramide is a natural regulatory ligand of p53 in cellular stress response. Nat Commun. 2018 10 08; 9(1):4149.
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DNA interactions of non-chelating tinidazole-based coordination compounds and their structural, redox and cytotoxic properties. Dalton Trans. 2018 Jun 05; 47(22):7551-7560.
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The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168. Nat Cell Biol. 2018 03; 20(3):320-331.