Hepatocyte Nuclear Factor 3-alpha
"Hepatocyte Nuclear Factor 3-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A forkhead transcription factor that is an essential activator of GLUCAGON gene expression.
Descriptor ID |
D051541
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MeSH Number(s) |
D12.776.260.262.750 D12.776.260.950.249.500 D12.776.660.352.750 D12.776.930.318.750 D12.776.930.977.249.500
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Concept/Terms |
Hepatocyte Nuclear Factor 3-alpha- Hepatocyte Nuclear Factor 3-alpha
- Hepatocyte Nuclear Factor 3 alpha
- HNF-3alpha Protein
- HNF 3alpha Protein
- Forkhead Box A1 Protein
- Hepatocyte Nuclear Factor 3alpha
- HNF-3A Transcription Factor
- HNF 3A Transcription Factor
- Transcription Factor, HNF-3A
- Hepatocyte-Enriched Transcription Factor HNF-3A
- Hepatocyte Enriched Transcription Factor HNF 3A
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Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 3-alpha".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 3-alpha".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 3-alpha" by people in this website by year, and whether "Hepatocyte Nuclear Factor 3-alpha" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 3-alpha" by people in Profiles.
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FoxA factors: the chromatin key and doorstop essential for liver development and function. Genes Dev. 2020 08 01; 34(15-16):1003-1004.
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Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem. 2010 May 21; 285(21):16135-44.
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Insulin and epidermal growth factor suppress basal glucose-6-phosphatase catalytic subunit gene transcription through overlapping but distinct mechanisms. Biochem J. 2009 Jan 15; 417(2):611-20.
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Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors. Hepatology. 2004 Apr; 39(4):1038-47.
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An efficient method to successively introduce transgenes into a given genomic locus in the mouse. BMC Dev Biol. 2001; 1:10.
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Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice. Proc Natl Acad Sci U S A. 1999 Aug 31; 96(18):10152-7.
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Regulation of a transcription factor network required for differentiation and metabolism. Science. 1998 Jul 31; 281(5377):692-5.