Antigen-Presenting Cells

"Antigen-Presenting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.

Descriptor ID	D000938
MeSH Number(s)	A11.066 A15.382.066
Concept/Terms	Antigen-Presenting Cells Antigen-Presenting Cells Antigen Presenting Cells Antigen-Presenting Cell Cell, Antigen-Presenting Cells, Antigen-Presenting Accessory Cells, Immunologic Immunologic Accessory Cells Cells, Immunologic Accessory Immunologic Accessory Cell Accessory Cell, Immunologic Cell, Immunologic Accessory

Below are MeSH descriptors whose meaning is more general than "Antigen-Presenting Cells".

Anatomy [A]
Cells [A11]
Antigen-Presenting Cells [A11.066]
Hemic and Immune Systems [A15]
Immune System [A15.382]
Antigen-Presenting Cells [A15.382.066]

Below are MeSH descriptors whose meaning is more specific than "Antigen-Presenting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigen-Presenting Cells" by people in this website by year, and whether "Antigen-Presenting Cells" was a major or minor topic of these publications.

Bar chart showing 34 publications over 23 distinct years, with a maximum of 3 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	1	2
1996	1	0	1
1997	1	1	2
1998	0	1	1
1999	0	2	2
2003	0	1	1
2004	0	2	2
2005	0	1	1
2006	0	2	2
2007	1	0	1
2008	1	2	3
2009	0	1	1
2010	1	0	1
2012	1	0	1
2013	0	1	1
2014	0	1	1
2015	0	2	2
2016	0	1	1
2017	0	2	2
2018	1	1	2
2019	1	0	1
2020	0	1	1
2021	1	1	2

Below are the most recent publications written about "Antigen-Presenting Cells" by people in Profiles.

Szopa IM, Granica M, Bujak JK, Labedz A, Blaszczyk M, Paulos CM, Majchrzak-Kuligowska K. Effective Activation and Expansion of Canine Lymphocytes Using a Novel Nano-Sized Magnetic Beads Approach. Front Immunol. 2021; 12:604066.

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Wu Y, Tang CA, Mealer C, Bastian D, Hanief Sofi M, Tian L, Schutt S, Choi HJ, Ticer T, Zhang M, Sui X, Huang L, Mellor AL, Hu CA, Yu XZ. STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function. Cell Mol Immunol. 2021 03; 18(3):632-643.

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Zhao D, Hajiaghamohseni LM, Liu X, Szulc ZM, Bai A, Bielawska A, Norris JS, Reddy SV, Hannun YA, Haque A. Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis. Cytokine. 2020 11; 135:155219.

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Abelin JG, Harjanto D, Malloy M, Suri P, Colson T, Goulding SP, Creech AL, Serrano LR, Nasir G, Nasrullah Y, McGann CD, Velez D, Ting YS, Poran A, Rothenberg DA, Chhangawala S, Rubinsteyn A, Hammerbacher J, Gaynor RB, Fritsch EF, Greshock J, Oslund RC, Barthelme D, Addona TA, Arieta CM, Rooney MS. Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction. Immunity. 2019 10 15; 51(4):766-779.e17.

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Burrello C, Garavaglia F, Cribiù FM, Ercoli G, Lopez G, Troisi J, Colucci A, Guglietta S, Carloni S, Guglielmetti S, Taverniti V, Nizzoli G, Bosari S, Caprioli F, Rescigno M, Facciotti F. Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells. Nat Commun. 2018 12 05; 9(1):5184.

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Wang JC, Bolger-Munro M, Gold MR. Imaging the Interactions Between B Cells and Antigen-Presenting Cells. Methods Mol Biol. 2018; 1707:131-161.

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Pandey MK, Burrow TA, Rani R, Martin LJ, Witte D, Setchell KD, Mckay MA, Magnusen AF, Zhang W, Liou B, Köhl J, Grabowski GA. Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease. Nature. 2017 03 02; 543(7643):108-112.

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Wang JC, Lee JY, Christian S, Dang-Lawson M, Pritchard C, Freeman SA, Gold MR. The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. J Cell Sci. 2017 03 15; 130(6):1094-1109.

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Badawy AA, Namboodiri AM, Moffett JR. The end of the road for the tryptophan depletion concept in pregnancy and infection. Clin Sci (Lond). 2016 08 01; 130(15):1327-33.

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Klein T, Fung SY, Renner F, Blank MA, Dufour A, Kang S, Bolger-Munro M, Scurll JM, Priatel JJ, Schweigler P, Melkko S, Gold MR, Viner RI, Régnier CH, Turvey SE, Overall CM. The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-?B signalling. Nat Commun. 2015 Nov 03; 6:8777.

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