Angiopoietin-1

"Angiopoietin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.

Descriptor ID	D042683
MeSH Number(s)	D12.644.276.100.100.100 D12.776.467.100.100.100 D23.529.100.100.100
Concept/Terms	Angiopoietin-1 Angiopoietin-1 Angiopoietin 1

Below are MeSH descriptors whose meaning is more general than "Angiopoietin-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Angiogenic Proteins [D12.644.276.100]
Angiopoietins [D12.644.276.100.100]
Angiopoietin-1 [D12.644.276.100.100.100]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Angiogenic Proteins [D12.776.467.100]
Angiopoietins [D12.776.467.100.100]
Angiopoietin-1 [D12.776.467.100.100.100]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Angiogenic Proteins [D23.529.100]
Angiopoietins [D23.529.100.100]
Angiopoietin-1 [D23.529.100.100.100]

Below are MeSH descriptors whose meaning is related to "Angiopoietin-1".

Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Angiopoietin-1" by people in this website by year, and whether "Angiopoietin-1" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2004	0	1	1
2006	0	1	1
2007	0	1	1
2010	1	0	1
2012	1	0	1
2014	0	1	1
2016	1	1	2
2018	0	1	1
2021	0	1	1

Below are the most recent publications written about "Angiopoietin-1" by people in Profiles.

Peplinski BS, Houston BA, Bluemke DA, Kawut SM, Kolb TM, Kronmal RA, Lima JAC, Ralph DD, Rayner SG, Steinberg ZL, Tedford RJ, Leary PJ. Associations of Angiopoietins With Heart Failure Incidence and Severity. J Card Fail. 2021 07; 27(7):786-795.

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Lal C, Hardiman G, Kumbhare S, Strange C. Proteomic biomarkers of cognitive impairment in obstructive sleep apnea syndrome. Sleep Breath. 2019 Mar; 23(1):251-257.

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Dalton AC, Shlamkovitch T, Papo N, Barton WA. Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin. PLoS One. 2016; 11(10):e0163732.

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Attia EF, Jolley SE, Crothers K, Schnapp LM, Liles WC. Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Elevated in Bronchoalveolar Lavage Fluid of Patients with Acute Respiratory Distress Syndrome. PLoS One. 2016; 11(2):e0149687.

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Soliman S, Ishrat T, Pillai A, Somanath PR, Ergul A, El-Remessy AB, Fagan SC. Candesartan induces a prolonged proangiogenic effect and augments endothelium-mediated neuroprotection after oxygen and glucose deprivation: role of vascular endothelial growth factors A and B. J Pharmacol Exp Ther. 2014 Jun; 349(3):444-57.

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Ngok SP, Geyer R, Liu M, Kourtidis A, Agrawal S, Wu C, Seerapu HR, Lewis-Tuffin LJ, Moodie KL, Huveldt D, Marx R, Baraban JM, Storz P, Horowitz A, Anastasiadis PZ. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. J Cell Biol. 2012 Dec 24; 199(7):1103-15.

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Thompson SD, Sudman M, Ramos PS, Marion MC, Ryan M, Tsoras M, Weiler T, Wagner M, Keddache M, Haas JP, Mueller C, Prahalad S, Bohnsack J, Wise CA, Punaro M, Zhang D, Rosé CD, Comeau ME, Divers J, Glass DN, Langefeld CD. The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1. Arthritis Rheum. 2010 Nov; 62(11):3265-76.

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Dickson PV, Hamner JB, Streck CJ, Ng CY, McCarville MB, Calabrese C, Gilbertson RJ, Stewart CF, Wilson CM, Gaber MW, Pfeffer LM, Skapek SX, Nathwani AC, Davidoff AM. Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculature. Mol Cancer Res. 2007 Jun; 5(6):531-42.

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Liang XB, Ma LJ, Naito T, Wang Y, Madaio M, Zent R, Pozzi A, Fogo AB. Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth. J Am Soc Nephrol. 2006 Jul; 17(7):1886-95.

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Kertesz N, Wu J, Chen TH, Sucov HM, Wu H. The role of erythropoietin in regulating angiogenesis. Dev Biol. 2004 Dec 01; 276(1):101-10.

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