alpha 1-Antitrypsin Deficiency
"alpha 1-Antitrypsin Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Deficiency of the protease inhibitor ALPHA 1-ANTITRYPSIN that manifests primarily as PULMONARY EMPHYSEMA and LIVER CIRRHOSIS.
| Descriptor ID |
D019896
|
| MeSH Number(s) |
C06.552.074 C08.381.112 C16.320.060 C23.550.325.500.500
|
| Concept/Terms |
alpha 1-Antitrypsin Deficiency- alpha 1-Antitrypsin Deficiency
- Deficiencies, alpha 1-Antitrypsin
- Deficiency, alpha 1-Antitrypsin
- alpha 1 Antitrypsin Deficiency
- alpha 1-Antitrypsin Deficiencies
|
Below are MeSH descriptors whose meaning is more general than "alpha 1-Antitrypsin Deficiency".
Below are MeSH descriptors whose meaning is more specific than "alpha 1-Antitrypsin Deficiency".
This graph shows the total number of publications written about "alpha 1-Antitrypsin Deficiency" by people in this website by year, and whether "alpha 1-Antitrypsin Deficiency" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 6 | 0 | 6 |
| 2015 | 6 | 0 | 6 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha 1-Antitrypsin Deficiency" by people in Profiles.
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Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease. EBioMedicine. 2022 Oct; 84:104262.
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Alpha-1 Antitrypsin Augmentation Therapy Improves Survival in Severely Deficient Patients with Predicted FEV1 Between 10% and 60%: A Retrospective Analysis of the NHLBI Alpha-1 Antitrypsin Deficiency Registry. Int J Chron Obstruct Pulmon Dis. 2020; 15:3193-3199.
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Alpha-1 Antitrypsin Deficiency Associated COPD. Clin Chest Med. 2020 09; 41(3):339-345.
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Alpha1-Antitrypsin Deficiency: Transition of Care for the Child With AAT Deficiency into Adulthood. Curr Pediatr Rev. 2019; 15(1):53-61.
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Anti-Proteases and Alpha-1 Antitrypsin Augmentation Therapy. Respir Care. 2018 Jun; 63(6):690-698.
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COPD in individuals with the PiMZ alpha-1 antitrypsin genotype. Eur Respir Rev. 2017 Dec 31; 26(146).
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Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy. J Biol Chem. 2015 Dec 11; 290(50):29742-57.
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Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol. Ann Am Thorac Soc. 2015 Oct; 12(10):1551-60.
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Treatment of Alpha-1 Antitrypsin Deficiency. Semin Respir Crit Care Med. 2015 Aug; 36(4):470-7.
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The United States Alpha-1 Foundation Research Registry: Genesis, Impact and Future. COPD. 2015 May; 12 Suppl 1:42-5.