Metformin

"Metformin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)

Descriptor ID	D008687
MeSH Number(s)	D02.078.370.141.450
Concept/Terms	Metformin Metformin Dimethylbiguanidine Dimethylguanylguanidine Glucophage Glucophage Metformin Hydrochloride Metformin Hydrochloride Hydrochloride, Metformin Metformin HCl HCl, Metformin

Below are MeSH descriptors whose meaning is more general than "Metformin".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amidines [D02.078]
Guanidines [D02.078.370]
Biguanides [D02.078.370.141]
Metformin [D02.078.370.141.450]

Below are MeSH descriptors whose meaning is related to "Metformin".

Below are MeSH descriptors whose meaning is more specific than "Metformin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Metformin" by people in this website by year, and whether "Metformin" was a major or minor topic of these publications.

Bar chart showing 53 publications over 20 distinct years, with a maximum of 6 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	1	0	1
1997	0	1	1
2004	0	1	1
2006	1	0	1
2007	0	1	1
2008	0	2	2
2009	3	1	4
2010	3	0	3
2011	0	1	1
2012	1	0	1
2013	1	5	6
2014	2	3	5
2015	3	1	4
2016	0	1	1
2017	4	0	4
2018	0	3	3
2019	2	3	5
2020	3	0	3
2021	3	1	4
2022	2	0	2

Below are the most recent publications written about "Metformin" by people in Profiles.

Ferri-Guerra J, Aparicio-Ugarriza R, Mohammed YN, Ysea O, Florez H, Ruiz JG. Propensity Score Matching to Determine the Impact of Metformin on All-Cause Mortality in Older Veterans with Diabetes Mellitus. South Med J. 2022 03; 115(3):208-213.

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Pollack BE, Barbaro RP, Selewski DT, Carlton EF. Lactic acidosis and multisystem organ failure following ibuprofen overdose requiring haemodialysis. BMJ Case Rep. 2022 Feb 07; 15(2).

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Palatnik A, Harrison RK, Thakkar MY, Walker RJ, Egede LE. Correlates of Insulin Selection as a First-Line Pharmacological Treatment for Gestational Diabetes. Am J Perinatol. 2022 01; 39(1):8-15.

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Schwartz AV, Pan Q, Aroda VR, Crandall JP, Kriska A, Piromalli C, Wallia A, Temprosa M, Florez H. Long-term effects of lifestyle and metformin interventions in DPP on bone density. Osteoporos Int. 2021 Nov; 32(11):2279-2287.

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Hazuda HP, Pan Q, Florez H, Luchsinger JA, Crandall JP, Venditti EM, Golden SH, Kriska AM, Bray GA. Association of Intensive Lifestyle and Metformin Interventions With Frailty in the Diabetes Prevention Program Outcomes Study. J Gerontol A Biol Sci Med Sci. 2021 04 30; 76(5):929-936.

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Timmons JG, Greenlaw N, Boyle JG, Chaturvedi N, Ford I, Brouwers MCGJ, Tillin T, Hramiak I, Hughes AD, Jenkins AJ, Klein BEK, Klein R, Ooi TC, Rossing P, Stehouwer CDA, Sattar N, Colhoun HM, Petrie JR. Metformin and carotid intima-media thickness in never-smokers with type 1 diabetes: The REMOVAL trial. Diabetes Obes Metab. 2021 06; 23(6):1371-1378.

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Aroda VR, Christophi CA, Edelstein SL, Perreault L, Kim C, Golden SH, Horton E, Mather KJ. Circulating sex hormone binding globulin levels are modified with intensive lifestyle intervention, but their changes did not independently predict diabetes risk in the Diabetes Prevention Program. BMJ Open Diabetes Res Care. 2020 12; 8(2).

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Kriska AM, Rockette-Wagner B, Edelstein SL, Bray GA, Delahanty LM, Hoskin MA, Horton ES, Venditti EM, Knowler WC. The Impact of Physical Activity on the Prevention of Type 2 Diabetes: Evidence and Lessons Learned From the Diabetes Prevention Program, a Long-Standing Clinical Trial Incorporating Subjective and Objective Activity Measures. Diabetes Care. 2021 01; 44(1):43-49.

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Sivitz WI, Phillips LS, Wexler DJ, Fortmann SP, Camp AW, Tiktin M, Perez M, Craig J, Hollander PA, Cherrington A, Aroda VR, Tan MH, Krakoff J, Rasouli N, Butera NM, Younes N. Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight. Diabetes Care. 2020 05; 43(5):940-947.

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Merino J, Jablonski KA, Mercader JM, Kahn SE, Chen L, Harden M, Delahanty LM, Araneta MRG, Walford GA, Jacobs SBR, Ibebuogu UN, Franks PW, Knowler WC, Florez JC. Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors. Diabetes. 2020 01; 69(1):112-120.

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