"Amidines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. Amidines include carboxamidines, sulfinamidines and phosphinamidines.
| Descriptor ID |
D000578
|
| MeSH Number(s) |
D02.078
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Amidines".
Below are MeSH descriptors whose meaning is more specific than "Amidines".
This graph shows the total number of publications written about "Amidines" by people in this website by year, and whether "Amidines" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amidines" by people in Profiles.
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The induction of microRNA-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest. PLoS One. 2013; 8(1):e53791.
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Role of inducible nitric oxide synthase in mitochondrial depolarization and graft injury after transplantation of fatty livers. Free Radic Biol Med. 2012 Jul 15; 53(2):250-9.
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The development of N-a-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-a-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors. J Med Chem. 2011 Oct 13; 54(19):6919-35.
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Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors. J Med Chem. 2010 Apr 08; 53(7):2766-78.
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Association of ABCA2 expression with determinants of Alzheimer's disease. FASEB J. 2004 Jul; 18(10):1129-31.
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Susceptibility to hepatic oxidative stress in rabbits fed different animal and plant fats. J Am Coll Nutr. 1996 Jun; 15(3):289-94.