"Squalene Monooxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.
| Descriptor ID |
D050603
|
| MeSH Number(s) |
D08.811.682.690.708.749
|
| Concept/Terms |
Squalene Monooxygenase- Squalene Monooxygenase
- Monooxygenase, Squalene
- Squalene Epoxidase
- Epoxidase, Squalene
- Squalene Monooxygenase (2,3-Epoxidizing)
|
Below are MeSH descriptors whose meaning is more general than "Squalene Monooxygenase".
Below are MeSH descriptors whose meaning is more specific than "Squalene Monooxygenase".
This graph shows the total number of publications written about "Squalene Monooxygenase" by people in this website by year, and whether "Squalene Monooxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Squalene Monooxygenase" by people in Profiles.
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Arabidopsis thaliana squalene epoxidase 1 is essential for root and seed development. J Biol Chem. 2007 Jun 08; 282(23):17002-13.