Phenylalanine Hydroxylase
"Phenylalanine Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.
| Descriptor ID |
D010651
|
| MeSH Number(s) |
D08.811.682.690.708.601
|
| Concept/Terms |
Phenylalanine Hydroxylase- Phenylalanine Hydroxylase
- Hydroxylase, Phenylalanine
- Phenylalanine 4-Hydroxylase
- 4-Hydroxylase, Phenylalanine
- Phenylalanine 4 Hydroxylase
- Phenylalanine 4-Monooxygenase
- 4-Monooxygenase, Phenylalanine
- Phenylalanine 4 Monooxygenase
|
Below are MeSH descriptors whose meaning is more general than "Phenylalanine Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Phenylalanine Hydroxylase".
This graph shows the total number of publications written about "Phenylalanine Hydroxylase" by people in this website by year, and whether "Phenylalanine Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phenylalanine Hydroxylase" by people in Profiles.
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A limited spectrum of phenylalanine hydroxylase mutations is observed in phenylketonuria patients in western Poland and implications for treatment with 6R tetrahydrobiopterin. J Hum Genet. 2009 Jun; 54(6):335-9.
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Biochemical characterization of mutant phenylalanine hydroxylase enzymes and correlation with clinical presentation in hyperphenylalaninaemic patients. J Inherit Metab Dis. 2009 Feb; 32(1):10-21.
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Mutations in the phenylalanine hydroxylase gene identified in 95 patients with phenylketonuria using novel systems of mutation scanning and specific genotyping based upon thermal melt profiles. Mol Genet Metab. 2007 Jul; 91(3):218-27.