Antiphospholipid Syndrome

"Antiphospholipid Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).

Descriptor ID	D016736
MeSH Number(s)	C20.111.197
Concept/Terms	Antiphospholipid Syndrome Antiphospholipid Syndrome Syndrome, Antiphospholipid Hughes Syndrome Syndrome, Hughes Antiphospholipid Antibody Syndrome Antibody Syndrome, Antiphospholipid Antiphospholipid Antibody Syndromes Syndrome, Antiphospholipid Antibody Anti-Phospholipid Antibody Syndrome Anti Phospholipid Antibody Syndrome Antibody Syndrome, Anti-Phospholipid Syndrome, Anti-Phospholipid Antibody Anti-Phospholipid Syndrome Anti Phospholipid Syndrome Syndrome, Anti-Phospholipid

Below are MeSH descriptors whose meaning is more general than "Antiphospholipid Syndrome".

Diseases [C]
Immune System Diseases [C20]
Autoimmune Diseases [C20.111]
Antiphospholipid Syndrome [C20.111.197]

Below are MeSH descriptors whose meaning is related to "Antiphospholipid Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Antiphospholipid Syndrome".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antiphospholipid Syndrome" by people in this website by year, and whether "Antiphospholipid Syndrome" was a major or minor topic of these publications.

Bar chart showing 22 publications over 14 distinct years, with a maximum of 3 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1996	1	1	2
1997	1	1	2
1998	0	1	1
1999	1	0	1
2000	1	1	2
2003	1	0	1
2004	1	0	1
2008	2	0	2
2009	2	1	3
2017	0	1	1
2018	1	0	1
2019	1	1	2
2021	2	0	2

Below are the most recent publications written about "Antiphospholipid Syndrome" by people in Profiles.

Chu H, Sacharidou A, Nguyen A, Li C, Chambliss KL, Salmon JE, Shen YM, Lo J, Leone GW, Herz J, Hui DY, Marciano DK, Abrahams VM, Natale BV, Montalbano AP, Xiao X, Xu L, Natale DR, Shaul PW, Mineo C. Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome. Circ Res. 2021 09 17; 129(7):735-750.

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Hollerbach A, Müller-Calleja N, Pedrosa D, Canisius A, Sprinzl MF, Falter T, Rossmann H, Bodenstein M, Werner C, Sagoschen I, Münzel T, Schreiner O, Sivanathan V, Reuter M, Niermann J, Galle PR, Teyton L, Ruf W, Lackner KJ. Pathogenic lipid-binding antiphospholipid antibodies are associated with severity of COVID-19. J Thromb Haemost. 2021 09; 19(9):2335-2347.

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Mendel A, Bernatsky S, Pineau CA, St-Pierre Y, Hanly JG, Urowitz MB, Clarke AE, Romero-Diaz J, Gordon C, Bae SC, Wallace DJ, Merrill JT, Buyon J, Isenberg DA, Rahman A, Ginzler EM, Petri M, Dooley MA, Fortin P, Gladman DD, Steinsson K, Ramsey-Goldman R, Khamashta MA, Aranow C, Mackay M, Alarcón G, Manzi S, Nived O, Jönsen A, Zoma AA, van Vollenhoven RF, Ramos-Casals M, Ruiz-Irastorza G, Lim S, Kalunian KC, Inanc M, Kamen DL, Peschken CA, Jacobsen S, Askanase A, Sanchez-Guerrero J, Bruce IN, Costedoat-Chalumeau N, Vinet E. Use of combined hormonal contraceptives among women with systemic lupus erythematosus with and without medical contraindications to oestrogen. Rheumatology (Oxford). 2019 07 01; 58(7):1259-1267.

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Hollerbach A, Müller-Calleja N, Ritter S, Häuser F, Canisius A, Orning C, Jurk K, Lackner KJ. Platelet Activation by Antiphospholipid Antibodies Depends on Epitope Specificity and is Prevented by mTOR Inhibitors. Thromb Haemost. 2019 Jul; 119(7):1147-1153.

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Bevill BT, Argula RG, Gilkeson GC, Kim NH. A Man with Severe Pulmonary Hypertension and Right Ventricular Failure. Ann Am Thorac Soc. 2018 12; 15(12):1472-1476.

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Binder SR, Litwin CM. Anti-phospholipid Antibodies and Smoking: An Overview. Clin Rev Allergy Immunol. 2017 Aug; 53(1):1-13.

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Ede K, Hwang KK, Wu CC, Wu M, Yang YH, Lin WS, Chien D, Chen PC, Tsao BP, McCurdy DK, Chen PP. Plasmin immunization preferentially induces potentially prothrombotic IgG anticardiolipin antibodies in MRL/MpJ mice. Arthritis Rheum. 2009 Oct; 60(10):3108-17.

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Rajamani K, Chaturvedi S, Jin Z, Homma S, Brey RL, Tilley BC, Sacco RL, Thompson JL, Mohr JP, Levine SR. Patent foramen ovale, cardiac valve thickening, and antiphospholipid antibodies as risk factors for subsequent vascular events: the PICSS-APASS study. Stroke. 2009 Jul; 40(7):2337-42.

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Ramanujam M, Kahn P, Huang W, Tao H, Madaio MP, Factor SM, Davidson A. Interferon-alpha treatment of female (NZW x BXSB)F(1) mice mimics some but not all features associated with the Yaa mutation. Arthritis Rheum. 2009 Apr; 60(4):1096-101.

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Kahn P, Ramanujam M, Bethunaickan R, Huang W, Tao H, Madaio MP, Factor SM, Davidson A. Prevention of murine antiphospholipid syndrome by BAFF blockade. Arthritis Rheum. 2008 Sep; 58(9):2824-34.

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