"Deoxyribonuclease I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.
| Descriptor ID |
D003850
|
| MeSH Number(s) |
D08.811.277.352.335.350.250
|
| Concept/Terms |
Deoxyribonuclease I- Deoxyribonuclease I
- DNAase I
- Pancreatic DNase
- DNase, Pancreatic
- Thymonuclease
- DNA Endonuclease
- Endonuclease, DNA
- DNase I
Nickase- Nickase
- DNA Nicking Enzyme
- Endonuclease I
|
Below are MeSH descriptors whose meaning is more general than "Deoxyribonuclease I".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonuclease I".
This graph shows the total number of publications written about "Deoxyribonuclease I" by people in this website by year, and whether "Deoxyribonuclease I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Deoxyribonuclease I" by people in Profiles.
-
At the Bedside: Neutrophil extracellular traps (NETs) as targets for biomarkers and therapies in autoimmune diseases. J Leukoc Biol. 2016 Feb; 99(2):265-78.
-
Helicobacter pylori-induced H,K-ATPase alpha-subunit gene repression is mediated by NF-kappaB p50 homodimer promoter binding. Am J Physiol Gastrointest Liver Physiol. 2008 Mar; 294(3):G795-807.
-
A Pseudomonas aeruginosa transcription factor that senses fatty acid structure. Mol Microbiol. 2007 Nov; 66(3):622-32.
-
Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med. 2007 Nov 15; 176(10):957-69.
-
NMR structure of AbhN and comparison with AbrBN: FIRST insights into the DNA binding promiscuity and specificity of AbrB-like transition state regulator proteins. J Biol Chem. 2006 Jul 28; 281(30):21399-21409.
-
Identification and characterization of the MDR1 promoter-enhancing factor 1 (MEF1) in the multidrug resistant HL60/VCR human acute myeloid leukemia cell line. Biochemistry. 2000 Jan 11; 39(1):194-204.
-
Receptor-mediated cellular entry of nuclear localizing anti-DNA antibodies via myosin 1. J Clin Invest. 1997 Jul 01; 100(1):25-31.
-
Spontaneously produced anti-DNA/DNase I autoantibodies modulate nuclear apoptosis in living cells. Eur J Immunol. 1996 Dec; 26(12):3035-41.
-
Anti-DNA antibodies bind to DNase I. J Exp Med. 1995 May 01; 181(5):1797-804.
-
Induction of anti-DNA antibodies in non autoimmune mice by immunization with a DNA-DNAase I complex. Clin Exp Rheumatol. 1995 Jan-Feb; 13(1):7-10.