"Protein Engineering" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that direct the synthesis of proteins with sought-after properties. Such procedures may include the design of MOLECULAR MODELS of proteins using COMPUTER GRAPHICS or other molecular modeling techniques; site-specific mutagenesis (MUTAGENESIS, SITE-SPECIFIC) of existing genes; and DIRECTED MOLECULAR EVOLUTION techniques to create new genes.
| Descriptor ID |
D015202
|
| MeSH Number(s) |
E05.393.420.601
|
| Concept/Terms |
Protein Engineering- Protein Engineering
- Engineering, Protein
- Genetic Engineering, Protein
- Engineering, Protein Genetic
- Protein Genetic Engineering
- Proteins, Genetic Engineering
- Genetic Engineering of Proteins
|
Below are MeSH descriptors whose meaning is more general than "Protein Engineering".
Below are MeSH descriptors whose meaning is more specific than "Protein Engineering".
This graph shows the total number of publications written about "Protein Engineering" by people in this website by year, and whether "Protein Engineering" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 4 | 5 |
| 2008 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Engineering" by people in Profiles.
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Khan I, O'Bryan JP. Probing RAS Function with Monobodies. Methods Mol Biol. 2021; 2262:281-302.
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Paquette DR, Mugridge JS, Weinberg DE, Gross JD. Application of a Schizosaccharomyces pombe Edc1-fused Dcp1-Dcp2 decapping enzyme for transcription start site mapping. RNA. 2018 02; 24(2):251-257.
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Bulutoglu B, Dooley K, Szilvay G, Blenner M, Banta S. Catch and Release: Engineered Allosterically Regulated ß-Roll Peptides Enable On/Off Biomolecular Recognition. ACS Synth Biol. 2017 09 15; 6(9):1732-1741.
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Harcum SW, Lee KH. CHO Cells Can Make More Protein. Cell Syst. 2016 11 23; 3(5):412-413.
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Samoudi M, Minuchehr Z, Harcum SW, Tabandeh F, Omid Yeganeh N, Khodabandeh M. Rational design of glycoengineered interferon-ß analogs with improved aggregation state: experimental validation. Protein Eng Des Sel. 2017 Jan; 30(1):23-30.
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Drennen B, Scheenstra JA, Yap JL, Chen L, Lanning ME, Roth BM, Wilder PT, Fletcher S. Structural Re-engineering of the a-Helix Mimetic JY-1-106 into Small Molecules: Disruption of the Mcl-1-Bak-BH3 Protein-Protein Interaction with 2,6-Di-Substituted Nicotinates. ChemMedChem. 2016 Apr 19; 11(8):827-33.
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Machleidt T, Woodroofe CC, Schwinn MK, Méndez J, Robers MB, Zimmerman K, Otto P, Daniels DL, Kirkland TA, Wood KV. NanoBRET--A Novel BRET Platform for the Analysis of Protein-Protein Interactions. ACS Chem Biol. 2015 Aug 21; 10(8):1797-804.
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Nair MS, Lee MM, Bonnegarde-Bernard A, Wallace JA, Dean DH, Ostrowski MC, Burry RW, Boyaka PN, Chan MK. Cry protein crystals: a novel platform for protein delivery. PLoS One. 2015; 10(6):e0127669.
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Nelson MH, Paulos CM. Novel immunotherapies for hematologic malignancies. Immunol Rev. 2015 Jan; 263(1):90-105.
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Thaxton JE, Li Z. To affinity and beyond: harnessing the T cell receptor for cancer immunotherapy. Hum Vaccin Immunother. 2014; 10(11):3313-21.