Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.

Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol. 2006 Nov; 4(11):e369.

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subject areas

Adipose Tissue, Brown
Adipose Tissue, White
Adrenergic Agents
Animals
Body Fat Distribution
Body Weight
Cold Temperature
Diet, Atherogenic
Electron Transport Chain Complex Proteins
Energy Metabolism
Female
Gene Expression Regulation
Heart
Heart Rate
Liver
Male
Metabolic Networks and Pathways
Mice
Mice, Knockout
Mitochondria
Mitochondria, Heart
Muscle, Skeletal
Norepinephrine
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Thermogenesis
Trans-Activators
Transcription Factors

authors with profiles

Sheldon E. Litwin