"Mitochondria" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
Descriptor ID |
D008928
|
MeSH Number(s) |
A11.284.430.214.190.875.564 A11.284.835.626
|
Concept/Terms |
Mitochondrial Contraction- Mitochondrial Contraction
- Contraction, Mitochondrial
- Contractions, Mitochondrial
- Mitochondrial Contractions
|
Below are MeSH descriptors whose meaning is more general than "Mitochondria".
Below are MeSH descriptors whose meaning is more specific than "Mitochondria".
This graph shows the total number of publications written about "Mitochondria" by people in this website by year, and whether "Mitochondria" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1995 | 3 | 1 | 4 |
1996 | 1 | 0 | 1 |
1997 | 2 | 2 | 4 |
1998 | 4 | 3 | 7 |
1999 | 5 | 5 | 10 |
2000 | 3 | 3 | 6 |
2001 | 3 | 2 | 5 |
2002 | 5 | 3 | 8 |
2003 | 6 | 8 | 14 |
2004 | 4 | 8 | 12 |
2005 | 9 | 5 | 14 |
2006 | 7 | 8 | 15 |
2007 | 14 | 4 | 18 |
2008 | 12 | 6 | 18 |
2009 | 10 | 4 | 14 |
2010 | 12 | 6 | 18 |
2011 | 7 | 4 | 11 |
2012 | 16 | 7 | 23 |
2013 | 10 | 14 | 24 |
2014 | 16 | 8 | 24 |
2015 | 13 | 6 | 19 |
2016 | 9 | 8 | 17 |
2017 | 14 | 8 | 22 |
2018 | 12 | 6 | 18 |
2019 | 13 | 8 | 21 |
2020 | 9 | 6 | 15 |
2021 | 6 | 5 | 11 |
2022 | 3 | 7 | 10 |
To return to the timeline,
click here.
Below are the most recent publications written about "Mitochondria" by people in Profiles.
-
ONC201-Induced Mitochondrial Dysfunction, Senescence-like Phenotype, and Sensitization of Cultured BT474 Human Breast Cancer Cells to TRAIL. Int J Mol Sci. 2022 Dec 08; 23(24).
-
Rho/SRF Inhibitor Modulates Mitochondrial Functions. Int J Mol Sci. 2022 Sep 29; 23(19).
-
A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria. J Biol Chem. 2022 09; 298(9):102336.
-
Characterization of TR-107, a novel chemical activator of the human mitochondrial protease ClpP. Pharmacol Res Perspect. 2022 08; 10(4):e00993.
-
Restricting a-synuclein transport into mitochondria by inhibition of a-synuclein-VDAC complexation as a potential therapeutic target for Parkinson's disease treatment. Cell Mol Life Sci. 2022 Jun 19; 79(7):368.
-
Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells. Biomed Pharmacother. 2022 Jun; 150:112928.
-
Intact mitochondrial substrate efflux is essential for prevention of tubular injury in a sex-dependent manner. JCI Insight. 2022 04 08; 7(7).
-
Secretory pathway Ca2+-ATPase SPCA2 regulates mitochondrial respiration and DNA damage response through store-independent calcium entry. Redox Biol. 2022 04; 50:102240.
-
Fast Determination of Mitochondrial Metabolism and Respiratory Complex Activity in Permeabilized and Intact Cells. Methods Mol Biol. 2022; 2497:1-10.
-
Neuroinflammation and Mitochondrial Dysfunction Link Social Stress to Depression. Curr Top Behav Neurosci. 2022; 54:59-93.