Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells.
Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells. Cancer Res. 1998 Apr 01; 58(7):1332-7.
-
Antineoplastic Agents, Hormonal
-
ATP-Binding Cassette Transporters
-
Carcinoma
-
Chromosomes, Human, Pair 9
-
Down-Regulation
-
Drug Resistance, Neoplasm
-
Estramustine
-
Female
-
Gene Amplification
-
Gene Expression Regulation, Neoplastic
-
Humans
-
In Situ Hybridization, Fluorescence
-
Oligonucleotides, Antisense
-
Ovarian Neoplasms
-
Polymerase Chain Reaction
-
RNA, Messenger
-
Transcription, Genetic
-
Tumor Cells, Cultured