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Doxorubicin generates a proapoptotic phenotype by phosphorylation of elongation factor 2.

Doxorubicin generates a proapoptotic phenotype by phosphorylation of elongation factor 2. Free Radic Biol Med. 2007 Nov 01; 43(9):1313-21.

View in: PubMed

subject areas
  • Apoptosis
  • CASP8 and FADD-Like Apoptosis Regulating Protein
  • Cell Cycle
  • Cell Line, Tumor
  • Deferoxamine
  • Doxorubicin
  • Drug Synergism
  • Free Radicals
  • Humans
  • Hydrogen Peroxide
  • Iron Chelating Agents
  • Male
  • Peptide Elongation Factor 2
  • Phenotype
  • Phosphorylation
  • Prostatic Neoplasms
  • Protein Biosynthesis
  • Protein Synthesis Inhibitors
  • TNF-Related Apoptosis-Inducing Ligand
  • X-Linked Inhibitor of Apoptosis Protein

authors with profiles
  • Paul J. McDermott
  • Christina Voelkel Johnson
  • Laura Simmons Spruill
  • Laura M. Kasman