"Iron Chelating Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.
| Descriptor ID |
D007502
|
| MeSH Number(s) |
D27.505.519.914.500.410 D27.720.832.500.410
|
| Concept/Terms |
Iron Chelating Agents- Iron Chelating Agents
- Agents, Iron Chelating
- Chelating Agents, Iron
- Iron Chelates
- Chelates, Iron
|
Below are MeSH descriptors whose meaning is more general than "Iron Chelating Agents".
Below are MeSH descriptors whose meaning is more specific than "Iron Chelating Agents".
This graph shows the total number of publications written about "Iron Chelating Agents" by people in this website by year, and whether "Iron Chelating Agents" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Iron Chelating Agents" by people in Profiles.
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A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria. J Biol Chem. 2022 09; 298(9):102336.
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Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial. Lancet Neurol. 2019 05; 18(5):428-438.
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The iron chelating agent, deferoxamine detoxifies Fe(Salen)-induced cytotoxicity. J Pharmacol Sci. 2017 Aug; 134(4):203-210.
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Ciclopirox enhances pancreatic islet health by modulating the unfolded protein response in diabetes. Pflugers Arch. 2016 11; 468(11-12):1957-1968.
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Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline. Free Radic Biol Med. 2016 08; 97:418-426.
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Medication adherence among pediatric patients with sickle cell disease: a systematic review. Pediatrics. 2014 Dec; 134(6):1175-83.
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Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes. Free Radic Biol Med. 2013 Oct; 63:243-53.
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Lysosomal signaling enhances mitochondria-mediated photodynamic therapy in A431 cancer cells: role of iron. Photochem Photobiol. 2012 Mar-Apr; 88(2):461-8.
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Rapid monitoring of iron-chelating therapy in thalassemia major by a new cardiovascular MR measure: the reduced transverse relaxation rate. NMR Biomed. 2011 Aug; 24(7):771-7.
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Lysosomal iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes. Toxicol Sci. 2010 Sep; 117(1):101-8.