"Minocycline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.
| Descriptor ID |
D008911
|
| MeSH Number(s) |
D02.455.426.559.847.562.900.550 D04.615.562.900.550
|
| Concept/Terms |
Minocycline Hydrochloride- Minocycline Hydrochloride
- Hydrochloride, Minocycline
- Minocycline Monohydrochloride
- Monohydrochloride, Minocycline
|
Below are MeSH descriptors whose meaning is more general than "Minocycline".
Below are MeSH descriptors whose meaning is more specific than "Minocycline".
This graph shows the total number of publications written about "Minocycline" by people in this website by year, and whether "Minocycline" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 3 | 0 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 3 | 0 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Minocycline" by people in Profiles.
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Adelusi OB, Ramachandran A, Lemasters JJ, Jaeschke H. The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice. Toxicol Appl Pharmacol. 2022 06 15; 445:116043.
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Warner AJ, Hathaway-Schrader JD, Lubker R, Davies C, Novince CM. Tetracyclines and bone: Unclear actions with potentially lasting effects. Bone. 2022 06; 159:116377.
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Cruz SL, Armenta-Reséndiz M, Carranza-Aguilar CJ, Galván EJ. Minocycline prevents neuronal hyperexcitability and neuroinflammation in medial prefrontal cortex, as well as memory impairment caused by repeated toluene inhalation in adolescent rats. Toxicol Appl Pharmacol. 2020 05 15; 395:114980.
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Hu J, Lemasters JJ. Suppression of iron mobilization from lysosomes to mitochondria attenuates liver injury after acetaminophen overdose in vivo in mice: Protection by minocycline. Toxicol Appl Pharmacol. 2020 04 01; 392:114930.
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Pradier M, Robineau O, Boucher A, Titecat M, Blondiaux N, Valette M, Loïez C, Beltrand E, Nguyen S, Dézeque H, Migaud H, Senneville E. Suppressive antibiotic therapy with oral tetracyclines for prosthetic joint infections: a retrospective study of 78 patients. Infection. 2018 Feb; 46(1):39-47.
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Fouda AY, Newsome AS, Spellicy S, Waller JL, Zhi W, Hess DC, Ergul A, Edwards DJ, Fagan SC, Switzer JA. Minocycline in Acute Cerebral Hemorrhage: An Early Phase Randomized Trial. Stroke. 2017 10; 48(10):2885-2887.
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Hu J, Kholmukhamedov A, Lindsey CC, Beeson CC, Jaeschke H, Lemasters JJ. Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline. Free Radic Biol Med. 2016 08; 97:418-426.
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Derrick C, Love BL, Sanasi-Bhola K. Successful treatment with ceftriaxone induction and minocycline maintenance for gastrointestinal Whipple's disease. J Antimicrob Chemother. 2016 Apr; 71(4):1123-5.
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Scheuer T, Brockmöller V, Blanco Knowlton M, Weitkamp JH, Ruhwedel T, Mueller S, Endesfelder S, Bührer C, Schmitz T. Oligodendroglial maldevelopment in the cerebellum after postnatal hyperoxia and its prevention by minocycline. Glia. 2015 Oct; 63(10):1825-39.
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Yan P, Zhu A, Liao F, Xiao Q, Kraft A, Gonzales E, Perez R, Greenberg SM, Holtzman D, Lee JM. Minocycline reduces spontaneous hemorrhage in mouse models of cerebral amyloid angiopathy. Stroke. 2015 Jun; 46(6):1633-1640.