"Lipofuscin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A naturally occurring lipid pigment with histochemical characteristics similar to ceroid. It accumulates in various normal tissues and apparently increases in quantity with age.
Descriptor ID |
D008062
|
MeSH Number(s) |
D10.460 D23.767.550
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lipofuscin".
Below are MeSH descriptors whose meaning is more specific than "Lipofuscin".
This graph shows the total number of publications written about "Lipofuscin" by people in this website by year, and whether "Lipofuscin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2011 | 2 | 0 | 2 |
2012 | 2 | 1 | 3 |
2013 | 3 | 0 | 3 |
2014 | 1 | 1 | 2 |
2015 | 4 | 1 | 5 |
2016 | 0 | 1 | 1 |
2017 | 2 | 0 | 2 |
2018 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lipofuscin" by people in Profiles.
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Relative Contributions of All-Trans and 11-Cis Retinal to Formation of Lipofuscin and A2E Accumulating in Mouse Retinal Pigment Epithelium. Invest Ophthalmol Vis Sci. 2021 02 01; 62(2):1.
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Recombinant Manganese Peroxidase Reduces A2E Burden in Age-Related and Stargardt's Macular Degeneration Models. Rejuvenation Res. 2018 Dec; 21(6):560-571.
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Interphotoreceptor retinoid-binding protein removes all-trans-retinol and retinal from rod outer segments, preventing lipofuscin precursor formation. J Biol Chem. 2017 11 24; 292(47):19356-19365.
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All-trans retinal levels and formation of lipofuscin precursors after bleaching in rod photoreceptors from wild type and Abca4-/- mice. Exp Eye Res. 2017 02; 155:121-127.
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Imaging mass spectrometry of the visual system: Advancing the molecular understanding of retina degenerations. Proteomics Clin Appl. 2016 Apr; 10(4):391-402.
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A2E and lipofuscin distributions in macaque retinal pigment epithelium are similar to human. Photochem Photobiol Sci. 2015 Oct; 14(10):1888-95.
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A2E and Lipofuscin. Prog Mol Biol Transl Sci. 2015; 134:449-63.
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Oxidation and Cognitive Impairment in the Aging Zebrafish. Gerontology. 2015; 62(1):47-57.
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Kinetics of rhodopsin's chromophore monitored in a single photoreceptor. Methods Mol Biol. 2015; 1271:327-43.
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The 11-cis Retinal Origins of Lipofuscin in the Retina. Prog Mol Biol Transl Sci. 2015; 134:e1-12.