Retinal Pigment Epithelium
"Retinal Pigment Epithelium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
| Descriptor ID |
D055213
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| MeSH Number(s) |
A09.371.670.500 A09.371.729.887
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinal Pigment Epithelium".
Below are MeSH descriptors whose meaning is more specific than "Retinal Pigment Epithelium".
This graph shows the total number of publications written about "Retinal Pigment Epithelium" by people in this website by year, and whether "Retinal Pigment Epithelium" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 3 | 3 | 6 |
| 2010 | 2 | 3 | 5 |
| 2011 | 5 | 0 | 5 |
| 2012 | 7 | 0 | 7 |
| 2013 | 4 | 1 | 5 |
| 2014 | 7 | 1 | 8 |
| 2015 | 9 | 2 | 11 |
| 2016 | 5 | 3 | 8 |
| 2017 | 3 | 1 | 4 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 1 | 4 |
| 2021 | 6 | 1 | 7 |
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Retinal Pigment Epithelium" by people in Profiles.
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West Nile Virus-Related Retinal Pigment Epithelium Changes on Multimodal Imaging. Ophthalmol Retina. 2023 01; 7(1):32.
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FoxP3 expression by retinal pigment epithelial cells: transcription factor with potential relevance for the pathology of age-related macular degeneration. J Neuroinflammation. 2022 Oct 22; 19(1):260.
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Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury. Exp Eye Res. 2021 11; 212:108755.
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Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. Int J Mol Sci. 2021 May 11; 22(10).
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Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration. Exp Eye Res. 2021 06; 207:108583.
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Subretinal Rather Than Intravitreal Adeno-Associated Virus-Mediated Delivery of a Complement Alternative Pathway Inhibitor Is Effective in a Mouse Model of RPE Damage. Invest Ophthalmol Vis Sci. 2021 04 01; 62(4):11.
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Mitochondrial C3a Receptor Activation in Oxidatively Stressed Epithelial Cells Reduces Mitochondrial Respiration and Metabolism. Front Immunol. 2021; 12:628062.
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Relative Contributions of All-Trans and 11-Cis Retinal to Formation of Lipofuscin and A2E Accumulating in Mouse Retinal Pigment Epithelium. Invest Ophthalmol Vis Sci. 2021 02 01; 62(2):1.
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Isolation of Mitochondria from Retinal Pigment Epithelial Cell Cultures and an Application of High-Resolution Respirometric Assay (XFe96 Seahorse Assay). Methods Mol Biol. 2021; 2277:423-431.
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Systemic Inflammation by Collagen-Induced Arthritis Affects the Progression of Age-Related Macular Degeneration Differently in Two Mouse Models of the Disease. Invest Ophthalmol Vis Sci. 2020 12 01; 61(14):11.