Phosphodiesterase 5 Inhibitors

"Phosphodiesterase 5 Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds that specifically inhibit PHOSPHODIESTERASE 5.

Descriptor ID	D058986
MeSH Number(s)	D27.505.519.389.735.500
Concept/Terms	Phosphodiesterase 5 Inhibitors Phosphodiesterase 5 Inhibitors Inhibitors, Phosphodiesterase 5 Phosphodiesterase Type 5 Inhibitors PDE-5 Inhibitors Inhibitors, PDE-5 PDE 5 Inhibitors PDE5 Inhibitors Inhibitors, PDE5

Below are MeSH descriptors whose meaning is more general than "Phosphodiesterase 5 Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Inhibitors [D27.505.519.389]
Phosphodiesterase Inhibitors [D27.505.519.389.735]
Phosphodiesterase 5 Inhibitors [D27.505.519.389.735.500]

Below are MeSH descriptors whose meaning is related to "Phosphodiesterase 5 Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Phosphodiesterase 5 Inhibitors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Phosphodiesterase 5 Inhibitors" by people in this website by year, and whether "Phosphodiesterase 5 Inhibitors" was a major or minor topic of these publications.

Bar chart showing 15 publications over 7 distinct years, with a maximum of 3 publications in 2012 and 2015 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	1	0	1
2012	0	3	3
2015	2	1	3
2016	1	2	3
2018	0	2	2
2019	1	0	1
2020	1	1	2

Below are the most recent publications written about "Phosphodiesterase 5 Inhibitors" by people in Profiles.

Kittipibul V, Blumer V, Angsubhakorn N, Hernandez GA, Chaparro S, Tedford RJ, Agarwal R. Phosphodiesterase-5 Inhibitors and Outcomes During Left Ventricular Assist Device Support: A Systematic Review and Meta-Analysis. J Card Fail. 2021 04; 27(4):477-485.

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Corum DG, Jenkins DP, Heslop JA, Tallent LM, Beeson GC, Barth JL, Schnellmann RG, Muise-Helmericks RC. PDE5 inhibition rescues mitochondrial dysfunction and angiogenic responses induced by Akt3 inhibition by promotion of PRC expression. J Biol Chem. 2020 12 25; 295(52):18091-18104.

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Goldberg DJ, Zak V, Goldstein BH, Schumacher KR, Rhodes J, Penny DJ, Petit CJ, Ginde S, Menon SC, Kim SH, Kim GB, Nowlen TT, DiMaria MV, Frischhertz BP, Wagner JB, McHugh KE, McCrindle BW, Shillingford AJ, Sabati AA, Yetman AT, John AS, Richmond ME, Files MD, Payne RM, Mackie AS, Davis CK, Shahanavaz S, Hill KD, Garg R, Jacobs JP, Hamstra MS, Woyciechowski S, Rathge KA, McBride MG, Frommelt PC, Russell MW, Urbina EM, Yeager JL, Pemberton VL, Stylianou MP, Pearson GD, Paridon SM. Results of the FUEL Trial. Circulation. 2020 02 25; 141(8):641-651.

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Goldberg DJ, Zak V, Goldstein BH, McCrindle BW, Menon SC, Schumacher KR, Payne RM, Rhodes J, McHugh KE, Penny DJ, Trachtenberg F, Hamstra MS, Richmond ME, Frommelt PC, Files MD, Yeager JL, Pemberton VL, Stylianou MP, Pearson GD, Paridon SM. Design and rationale of the Fontan Udenafil Exercise Longitudinal (FUEL) trial. Am Heart J. 2018 07; 201:1-8.

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Khalaf M, Chowdhary S, Elias PS, Castell D. Distal Esophageal Spasm: A Review. Am J Med. 2018 09; 131(9):1034-1040.

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Kowal-Bielecka O, Fransen J, Avouac J, Becker M, Kulak A, Allanore Y, Distler O, Clements P, Cutolo M, Czirjak L, Damjanov N, Del Galdo F, Denton CP, Distler JHW, Foeldvari I, Figelstone K, Frerix M, Furst DE, Guiducci S, Hunzelmann N, Khanna D, Matucci-Cerinic M, Herrick AL, van den Hoogen F, van Laar JM, Riemekasten G, Silver R, Smith V, Sulli A, Tarner I, Tyndall A, Welling J, Wigley F, Valentini G, Walker UA, Zulian F, Müller-Ladner U. Update of EULAR recommendations for the treatment of systemic sclerosis. Ann Rheum Dis. 2017 Aug; 76(8):1327-1339.

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Clavijo RI, Daskivich T, Kwan L, Bassett J, Keller T, Bennett C. Time course and predictors of use of erectile dysfunction treatment in a Veterans Affairs medical center. Int J Impot Res. 2016 Sep; 28(5):167-71.

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Morgan P, Keller R, Patel K. Evidence-Based Management of Vascular Malformations. Facial Plast Surg. 2016 Apr; 32(2):162-76.

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Hassoun PM, Zamanian RT, Damico R, Lechtzin N, Khair R, Kolb TM, Tedford RJ, Hulme OL, Housten T, Pisanello C, Sato T, Pullins EH, Corona-Villalobos CP, Zimmerman SL, Gashouta MA, Minai OA, Torres F, Girgis RE, Chin K, Mathai SC. Ambrisentan and Tadalafil Up-front Combination Therapy in Scleroderma-associated Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2015 Nov 01; 192(9):1102-10.

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Butts RJ, Chowdhury SM, Baker GH, Bandisode V, Savage AJ, Atz AM. Effect of Sildenafil on Pressure-Volume Loop Measures of Ventricular Function in Fontan Patients. Pediatr Cardiol. 2016 Jan; 37(1):184-91.

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