Inducible T-Cell Co-Stimulator Protein
"Inducible T-Cell Co-Stimulator Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory receptor that is specific for INDUCIBLE T-CELL CO-STIMULATOR LIGAND. The receptor is associated with a diverse array of immunologically-related effects including the increased synthesis of INTERLEUKIN 10 in REGULATORY T-LYMPHOCYTES and the induction of PERIPHERAL TOLERANCE.
| Descriptor ID |
D060889
|
| MeSH Number(s) |
D12.776.543.750.705.222.812 D23.050.301.264.894.580 D23.101.100.894.580
|
| Concept/Terms |
Inducible T-Cell Co-Stimulator Protein- Inducible T-Cell Co-Stimulator Protein
- Inducible T Cell Co Stimulator Protein
- Inducible Co-Stimulator (ICOS)
- Inducible T-Cell Co-Stimulator
- Co-Stimulator, Inducible T-Cell
- Inducible T Cell Co Stimulator
- T-Cell Co-Stimulator, Inducible
- Antigens, CD278
- CD278 Antigens
- CD278 Antigen
- Antigen, CD278
- Activation-Inducible Lymphocyte Immunomediatory Molecule
- Activation Inducible Lymphocyte Immunomediatory Molecule
- Inducible Costimulator (ICOS)
- ICOS Inducible T-Cell Co-Stimulator
- ICOS Inducible T Cell Co Stimulator
|
Below are MeSH descriptors whose meaning is more general than "Inducible T-Cell Co-Stimulator Protein".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Costimulatory and Inhibitory T-Cell Receptors [D12.776.543.750.705.222]
- Inducible T-Cell Co-Stimulator Protein [D12.776.543.750.705.222.812]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- Inducible T-Cell Co-Stimulator Protein [D23.050.301.264.894.580]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- Inducible T-Cell Co-Stimulator Protein [D23.101.100.894.580]
Below are MeSH descriptors whose meaning is more specific than "Inducible T-Cell Co-Stimulator Protein".
This graph shows the total number of publications written about "Inducible T-Cell Co-Stimulator Protein" by people in this website by year, and whether "Inducible T-Cell Co-Stimulator Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Inducible T-Cell Co-Stimulator Protein" by people in Profiles.
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Majchrzak K, Nelson MH, Bailey SR, Bowers JS, Yu XZ, Rubinstein MP, Himes RA, Paulos CM. Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic. Cancer Immunol Immunother. 2016 Mar; 65(3):247-59.
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Nelson MH, Kundimi S, Bowers JS, Rogers CE, Huff LW, Schwartz KM, Thyagarajan K, Little EC, Mehrotra S, Cole DJ, Rubinstein MP, Paulos CM. The inducible costimulator augments Tc17 cell responses to self and tumor tissue. J Immunol. 2015 Feb 15; 194(4):1737-47.
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Zhang Q, Wang H, Kantekure K, Paterson JC, Liu X, Schaffer A, Paulos C, Milone MC, Odum N, Turner S, Marafioti T, Wasik MA. Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS. Blood. 2011 Sep 15; 118(11):3062-71.
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Paulos CM, Carpenito C, Plesa G, Suhoski MM, Varela-Rohena A, Golovina TN, Carroll RG, Riley JL, June CH. The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells. Sci Transl Med. 2010 Oct 27; 2(55):55ra78.