Inducible T-Cell Co-Stimulator Protein
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Inducible T-Cell Co-Stimulator Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A costimulatory receptor that is specific for INDUCIBLE T-CELL CO-STIMULATOR LIGAND. The receptor is associated with a diverse array of immunologically-related effects including the increased synthesis of INTERLEUKIN 10 in REGULATORY T-LYMPHOCYTES and the induction of PERIPHERAL TOLERANCE.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D060889
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						| MeSH Number(s) | 
						
							 D12.776.543.750.705.222.812 D23.050.301.264.894.580 D23.101.100.894.580 
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						| Concept/Terms | 
						
							Inducible T-Cell Co-Stimulator Protein- Inducible T-Cell Co-Stimulator Protein
 - Inducible T Cell Co Stimulator Protein
 - Inducible Co-Stimulator (ICOS)
 - Inducible T-Cell Co-Stimulator
 - Co-Stimulator, Inducible T-Cell
 - Inducible T Cell Co Stimulator
 - T-Cell Co-Stimulator, Inducible
 - Antigens, CD278
 - CD278 Antigens
 - CD278 Antigen
 - Antigen, CD278
 - Activation-Inducible Lymphocyte Immunomediatory Molecule
 - Activation Inducible Lymphocyte Immunomediatory Molecule
 - Inducible Costimulator (ICOS)
 - ICOS Inducible T-Cell Co-Stimulator
 - ICOS Inducible T Cell Co Stimulator
 
  
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				Below are MeSH descriptors whose meaning is more general than "Inducible T-Cell Co-Stimulator Protein".
				
					
						- Chemicals and Drugs [D]
 - Amino Acids, Peptides, and Proteins [D12]
 - Proteins [D12.776]
 - Membrane Proteins [D12.776.543]
 - Receptors, Cell Surface [D12.776.543.750]
 - Receptors, Immunologic [D12.776.543.750.705]
 - Costimulatory and Inhibitory T-Cell Receptors [D12.776.543.750.705.222]
 - Inducible T-Cell Co-Stimulator Protein [D12.776.543.750.705.222.812]
 - Biological Factors [D23]
 - Antigens [D23.050]
 - Antigens, Surface [D23.050.301]
 - Antigens, Differentiation [D23.050.301.264]
 - Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
 - Inducible T-Cell Co-Stimulator Protein [D23.050.301.264.894.580]
 - Biomarkers [D23.101]
 - Antigens, Differentiation [D23.101.100]
 - Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
 - Inducible T-Cell Co-Stimulator Protein [D23.101.100.894.580]
 
					
				 
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Inducible T-Cell Co-Stimulator Protein".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Inducible T-Cell Co-Stimulator Protein" by people in this website by year, and whether "Inducible T-Cell Co-Stimulator Protein" was a major or minor topic of these publications. 
				
					
                    To see the data from this visualization as text, 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2010 | 0 | 1 | 1 | 
| 2011 | 1 | 0 | 1 | 
| 2015 | 1 | 0 | 1 | 
| 2016 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "Inducible T-Cell Co-Stimulator Protein" by people in Profiles.
						
					
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Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic. Cancer Immunol Immunother. 2016 Mar; 65(3):247-59.
															
								 
							
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The inducible costimulator augments Tc17 cell responses to self and tumor tissue. J Immunol. 2015 Feb 15; 194(4):1737-47.
															
								 
							
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Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS. Blood. 2011 Sep 15; 118(11):3062-71.
															
								 
							
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The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells. Sci Transl Med. 2010 Oct 27; 2(55):55ra78.