Methyl CpG Binding Domain

"Methyl CpG Binding Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A protein domain of about 70 amino acids in length that folds into a sandwich structure consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in eukaryotic DNA BINDING PROTEINS.

Descriptor ID	D000070593
MeSH Number(s)	G02.111.570.820.709.275.750.438
Concept/Terms	Methyl CpG Binding Domain Methyl CpG Binding Domain Methyl CpG DNA Binding Domain

Below are MeSH descriptors whose meaning is more general than "Methyl CpG Binding Domain".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Protein Conformation [G02.111.570.820.709]
Protein Structural Elements [G02.111.570.820.709.275]
Protein Domains [G02.111.570.820.709.275.750]
Methyl CpG Binding Domain [G02.111.570.820.709.275.750.438]

Below are MeSH descriptors whose meaning is related to "Methyl CpG Binding Domain".

Below are MeSH descriptors whose meaning is more specific than "Methyl CpG Binding Domain".

publications

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