"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
|
| MeSH Number(s) |
G02.111.570.820.709
|
| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
|
Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 6 | 6 |
| 1996 | 0 | 5 | 5 |
| 1997 | 3 | 3 | 6 |
| 1998 | 1 | 12 | 13 |
| 1999 | 0 | 9 | 9 |
| 2000 | 0 | 5 | 5 |
| 2001 | 0 | 10 | 10 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 9 | 9 |
| 2004 | 0 | 17 | 17 |
| 2005 | 4 | 14 | 18 |
| 2006 | 1 | 9 | 10 |
| 2007 | 1 | 11 | 12 |
| 2008 | 1 | 13 | 14 |
| 2009 | 2 | 12 | 14 |
| 2010 | 0 | 10 | 10 |
| 2011 | 0 | 9 | 9 |
| 2012 | 0 | 10 | 10 |
| 2013 | 1 | 8 | 9 |
| 2014 | 0 | 12 | 12 |
| 2015 | 1 | 12 | 13 |
| 2016 | 0 | 8 | 8 |
| 2017 | 1 | 15 | 16 |
| 2018 | 1 | 11 | 12 |
| 2019 | 0 | 17 | 17 |
| 2020 | 1 | 10 | 11 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Coevolution and smFRET Enhances Conformation Sampling and FRET Experimental Design in Tandem PDZ1-2 Proteins. J Phys Chem B. 2023 02 02; 127(4):884-898.
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Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity. Nat Commun. 2021 11 25; 12(1):6896.
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BION-2: Predicting Positions of Non-Specifically Bound Ions on Protein Surface by a Gaussian-Based Treatment of Electrostatics. Int J Mol Sci. 2020 Dec 29; 22(1).
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Amyloid Aggregation under the Lens of Liquid-Liquid Phase Separation. J Phys Chem Lett. 2021 Jan 14; 12(1):368-378.
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Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV-2. Bioconjug Chem. 2021 01 20; 32(1):215-223.
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Unraveling protein's structural dynamics: from configurational dynamics to ensemble switching guides functional mesoscale assemblies. Curr Opin Struct Biol. 2021 02; 66:129-138.
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Inhibition of RAS: proven and potential vulnerabilities. Biochem Soc Trans. 2020 10 30; 48(5):1831-1841.
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Automated and optimally FRET-assisted structural modeling. Nat Commun. 2020 10 26; 11(1):5394.
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Cautionary Tale of Using Tris(alkyl)phosphine Reducing Agents with NAD+-Dependent Enzymes. Biochemistry. 2020 09 15; 59(36):3285-3289.
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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone. Cell Rep. 2020 06 30; 31(13):107840.