"Calbindins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Calcium-binding proteins that are found in DISTAL KIDNEY TUBULES, INTESTINES, BRAIN, and other tissues where they bind, buffer and transport cytoplasmic calcium. Calbindins possess a variable number of EF-HAND MOTIFS which contain calcium-binding sites. Some isoforms are regulated by VITAMIN D.
| Descriptor ID |
D064026
|
| MeSH Number(s) |
D12.776.157.125.090
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Calbindins".
Below are MeSH descriptors whose meaning is more specific than "Calbindins".
This graph shows the total number of publications written about "Calbindins" by people in this website by year, and whether "Calbindins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
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Below are the most recent publications written about "Calbindins" by people in Profiles.
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Bobay BG, Stewart AL, Tucker AT, Thompson RJ, Varney KM, Cavanagh J. Structural insights into the calcium-dependent interaction between calbindin-D28K and caspase-3. FEBS Lett. 2012 Oct 19; 586(20):3582-9.
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Das A, Wallace G, Reiter RJ, Varma AK, Ray SK, Banik NL. Overexpression of melatonin membrane receptors increases calcium-binding proteins and protects VSC4.1 motoneurons from glutamate toxicity through multiple mechanisms. J Pineal Res. 2013 Jan; 54(1):58-68.
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Hobbs CA, Deterding LJ, Perera L, Bobay BG, Thompson RJ, Darden TA, Cavanagh J, Tomer KB. Structural characterization of the conformational change in calbindin-D28k upon calcium binding using differential surface modification analyzed by mass spectrometry. Biochemistry. 2009 Sep 15; 48(36):8603-14.
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Lockrow J, Prakasam A, Huang P, Bimonte-Nelson H, Sambamurti K, Granholm AC. Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model. Exp Neurol. 2009 Apr; 216(2):278-89.
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Kordys DR, Bobay BG, Thompson RJ, Venters RA, Cavanagh J. Peptide binding proclivities of calcium loaded calbindin-D28k. FEBS Lett. 2007 Oct 02; 581(24):4778-82.
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Trantham-Davidson H, Kröner S, Seamans JK. Dopamine modulation of prefrontal cortex interneurons occurs independently of DARPP-32. Cereb Cortex. 2008 Apr; 18(4):951-8.
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Kojetin DJ, Venters RA, Kordys DR, Thompson RJ, Kumar R, Cavanagh J. Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K). Nat Struct Mol Biol. 2006 Jul; 13(7):641-7.
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Hunter CL, Bachman D, Granholm AC. Minocycline prevents cholinergic loss in a mouse model of Down's syndrome. Ann Neurol. 2004 Nov; 56(5):675-88.
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Mulholland PJ, Harris BR, Wilkins LH, Self RL, Blanchard JA, Holley RC, Littleton JM, Prendergast MA. Opposing effects of ethanol and nicotine on hippocampal calbindin-D28k expression. Alcohol. 2003 Aug-Oct; 31(1-2):1-10.
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Venters RA, Benson LM, Craig TA, Bagu J, Paul KH, Kordys DR, Thompson R, Naylor S, Kumar R, Cavanagh J. The effects of Ca(2+) binding on the conformation of calbindin D(28K): a nuclear magnetic resonance and microelectrospray mass spectrometry study. Anal Biochem. 2003 Jun 01; 317(1):59-66.