"Osteonectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.
| Descriptor ID |
D015676
|
| MeSH Number(s) |
D12.776.157.125.715 D12.776.395.600
|
| Concept/Terms |
Osteonectin- Osteonectin
- SPARC Glycoprotein
- BM-40
- Basement Membrane Tumor Protein
- BM 40 Protein
|
Below are MeSH descriptors whose meaning is more general than "Osteonectin".
Below are MeSH descriptors whose meaning is more specific than "Osteonectin".
This graph shows the total number of publications written about "Osteonectin" by people in this website by year, and whether "Osteonectin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 3 | 0 | 3 |
| 2000 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 4 | 0 | 4 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 3 | 0 | 3 |
| 2010 | 4 | 1 | 5 |
| 2011 | 3 | 0 | 3 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 3 | 0 | 3 |
| 2016 | 3 | 0 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Osteonectin" by people in Profiles.
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Pten regulates collagen fibrillogenesis by fibroblasts through SPARC. PLoS One. 2021; 16(2):e0245653.
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SPARC production by bone marrow-derived cells contributes to myocardial fibrosis in pressure overload. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H604-H612.
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The Influence of the Extracellular Matrix in Inflammation: Findings from the SPARC-Null Mouse. Anat Rec (Hoboken). 2020 06; 303(6):1624-1629.
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Increased macrophage-derived SPARC precedes collagen deposition in myocardial fibrosis. Am J Physiol Heart Circ Physiol. 2018 07 01; 315(1):H92-H100.
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Production and purification of recombinant human SPARC. Methods Cell Biol. 2018; 143:335-345.
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SPARC and the N-propeptide of collagen I influence fibroblast proliferation and collagen assembly in the periodontal ligament. PLoS One. 2017; 12(2):e0173209.
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Pleiotropic roles of the matricellular protein Sparc in tendon maturation and ageing. Sci Rep. 2016 09 02; 6:32635.
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Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium. Am J Physiol Endocrinol Metab. 2016 06 01; 310(11):E1027-35.
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SPARC/osteonectin in mineralized tissue. Matrix Biol. 2016 May-Jul; 52-54:78-87.
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The role of secreted protein acidic and rich in cysteine (SPARC) in cardiac repair and fibrosis: Does expression of SPARC by macrophages influence outcomes? J Mol Cell Cardiol. 2016 04; 93:156-61.