"Uncoupling Protein 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial uncoupling protein that is expressed in heart and skeletal muscle tissues. It functions to regulate tissue respiration, energy balance, and THERMOGENESIS. Mutations in the UCP3 gene are associated with OBESITY.
| Descriptor ID |
D000071247
|
| MeSH Number(s) |
D12.776.157.530.937.598.875 D12.776.543.585.475.688.875 D12.776.543.585.937.696.875 D12.776.575.750.688.875
|
| Concept/Terms |
Uncoupling Protein 3- Uncoupling Protein 3
- Uncoupling Protein-3
- Solute Carrier Family 25 Member 9
- UCP3 Protein
- SLC25A9 Protein
- Mitochondrial Uncoupling Protein 3
|
Below are MeSH descriptors whose meaning is more general than "Uncoupling Protein 3".
Below are MeSH descriptors whose meaning is more specific than "Uncoupling Protein 3".
This graph shows the total number of publications written about "Uncoupling Protein 3" by people in this website by year, and whether "Uncoupling Protein 3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Uncoupling Protein 3" by people in Profiles.
-
Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia. J Natl Cancer Inst. 2015 Dec; 107(12):djv274.
-
Genetic loss of insulin receptors worsens cardiac efficiency in diabetes. J Mol Cell Cardiol. 2012 May; 52(5):1019-26.
-
Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome. Am J Physiol Endocrinol Metab. 2009 Jul; 297(1):E211-24.
-
Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women. J Nutr. 2009 Jun; 139(6):1073-81.
-
UCPs--unlikely calcium porters. Nat Cell Biol. 2008 Nov; 10(11):1235-7; author reply 1237-40.
-
Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. Diabetes. 2008 Nov; 57(11):2924-32.
-
Uncoupling protein 3 and human metabolism. J Clin Endocrinol Metab. 2006 Apr; 91(4):1226-8.
-
Role of UCP2 and UCP3 in nutrition and obesity. Nutrition. 2004 Jan; 20(1):139-44.
-
The role of uncoupling protein 3 in human physiology. J Clin Invest. 2003 Feb; 111(4):438-41.
-
Endogenous mutations in human uncoupling protein 3 alter its functional properties. FEBS Lett. 1999 Dec 31; 464(3):189-93.