"Uncoupling Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial uncoupling protein that is expressed in many tissues and exhibits the greatest expression in SKELETAL MUSCLE. It regulates mitochondrial ATP production and the generation of REACTIVE OXYGEN SPECIES.
| Descriptor ID |
D000071246
|
| MeSH Number(s) |
D12.776.157.530.937.598.750 D12.776.543.585.475.688.750 D12.776.543.585.937.696.750 D12.776.575.750.688.750
|
| Concept/Terms |
Uncoupling Protein 2- Uncoupling Protein 2
- Mitochondrial Uncoupling Protein 2
- SLC25A8 Protein
- UCP2 Protein
- Uncoupling Protein-2
- Solute Carrier Family 25 Member 8
|
Below are MeSH descriptors whose meaning is more general than "Uncoupling Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Uncoupling Protein 2".
This graph shows the total number of publications written about "Uncoupling Protein 2" by people in this website by year, and whether "Uncoupling Protein 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Uncoupling Protein 2" by people in Profiles.
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UCP2 knockout suppresses mouse skin carcinogenesis. Cancer Prev Res (Phila). 2015 Jun; 8(6):487-91.
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Mitochondrial uncoupling protein 2 induces cell cycle arrest and necrotic cell death. Metab Syndr Relat Disord. 2014 Mar; 12(2):132-42.
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Mitochondrial uncoupling protein-2 deficiency protects steatotic mouse hepatocytes from hypoxia/reoxygenation. Am J Physiol Gastrointest Liver Physiol. 2012 Feb 01; 302(3):G336-42.
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Vitamin E succinate enhances steatotic liver energy status and prevents oxidative damage following ischemia/reperfusion. Transplant Proc. 2009 Dec; 41(10):4094-8.
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Vitamin E succinate reduces ischemia/reperfusion injury in steatotic livers. Transplant Proc. 2008 Dec; 40(10):3327-9.
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UCPs--unlikely calcium porters. Nat Cell Biol. 2008 Nov; 10(11):1235-7; author reply 1237-40.
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Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. Diabetes. 2008 Nov; 57(11):2924-32.
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Mitochondrial uncoupling protein-2 mediates steatotic liver injury following ischemia/reperfusion. J Biol Chem. 2008 Mar 28; 283(13):8573-9.
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NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts. Am J Transplant. 2007 May; 7(5):1103-11.
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Obesity alters rat abdominal flap survival. Am Surg. 2006 Sep; 72(9):764-71; discussion 771-2.