Chitinase-3-Like Protein 1
"Chitinase-3-Like Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.
| Descriptor ID |
D000071451
|
| MeSH Number(s) |
D08.811.277.450.207.500 D12.776.503.070
|
| Concept/Terms |
Chitinase-3-Like Protein 1- Chitinase-3-Like Protein 1
- Chitinase 3 Like Protein 1
- Cartilage Glycoprotein 39
- Glycoprotein 39, Cartilage
- GP-39 Protein
- GP 39 Protein
- YLK-40 Protein
- YLK 40 Protein
- CHI3L1 Protein
- CGP-39 Protein
- CGP 39 Protein
|
Below are MeSH descriptors whose meaning is more general than "Chitinase-3-Like Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Chitinase-3-Like Protein 1".
This graph shows the total number of publications written about "Chitinase-3-Like Protein 1" by people in this website by year, and whether "Chitinase-3-Like Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chitinase-3-Like Protein 1" by people in Profiles.
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Malhotra R, Katz R, Jotwani V, Ambrosius WT, Raphael KL, Haley W, Rastogi A, Cheung AK, Freedman BI, Punzi H, Rocco MV, Ix JH, Shlipak MG. Urine Markers of Kidney Tubule Cell Injury and Kidney Function Decline in SPRINT Trial Participants with CKD. Clin J Am Soc Nephrol. 2020 03 06; 15(3):349-358.
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Bullen AL, Katz R, Lee AK, Anderson CAM, Cheung AK, Garimella PS, Jotwani V, Haley WE, Ishani A, Lash JP, Neyra JA, Punzi H, Rastogi A, Riessen E, Malhotra R, Parikh CR, Rocco MV, Wall BM, Bhatt UY, Shlipak MG, Ix JH, Estrella MM. The SPRINT trial suggests that markers of tubule cell function in the urine associate with risk of subsequent acute kidney injury while injury markers elevate after the injury. Kidney Int. 2019 08; 96(2):470-479.
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Jian J, Chen Y, Liberti R, Fu W, Hu W, Saunders-Pullman R, Pastores GM, Chen Y, Sun Y, Grabowski GA, Liu CJ. Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease. EBioMedicine. 2018 Feb; 28:251-260.