"Proof of Concept Study" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An empirical investigation which pertains to the development of prototypes or models that demonstrate the feasibility of novel concepts, ideas, principles, schema or their practical application.
Descriptor ID 
D000075082

MeSH Number(s) 
H01.770.644.578

Concept/Terms 
Proof of Concept Study Proof of Concept Study
 Concept Study Proof
 Study Proof, Concept
 Proof of Concept Investigation
 Concept Investigation Proof
 Investigation Proof, Concept
 Proof of Concept Research
 Concept Research Proof
 Concept Research Proofs
 Research Proof, Concept
 Proof of Concept Testing
 Concept Testing Proof
 Concept Testing Proofs
 Testing Proof, Concept
 Testing Proofs, Concept
 Proof of Concept Experiment
 Concept Experiment Proof
 Concept Experiment Proofs
 Experiment Proof, Concept
 Proof of Concept Approach
 Approach Proof, Concept
 Approach Proofs, Concept
 Concept Approach Proof
 Concept Approach Proofs
 Proof of Concept Studies
Proof of Concept Prototype Proof of Concept Prototype
 Concept Prototype Proof
 Concept Prototype Proofs
 Prototype Proof, Concept
 Proof of Concept Model
 Concept Model Proof
 Concept Model Proofs
 Model Proof, Concept
Proof of Concept Evaluation Proof of Concept Evaluation
 Concept Evaluation Proof
 Concept Evaluation Proofs
 Evaluation Proof, Concept
 Proof of Concept Demonstration
 Concept Demonstration Proof
 Demonstration Proof, Concept

Below are MeSH descriptors whose meaning is more general than "Proof of Concept Study".
Below are MeSH descriptors whose meaning is more specific than "Proof of Concept Study".
This graph shows the total number of publications written about "Proof of Concept Study" by people in this website by year, and whether "Proof of Concept Study" was a major or minor topic of these publications.
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Year  Major Topic  Minor Topic  Total 

2016  1  0  1 
2017  0  4  4 
2018  1  4  5 
2019  0  2  2 
2020  0  1  1 
2021  0  1  1 
2022  0  2  2 
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Below are the most recent publications written about "Proof of Concept Study" by people in Profiles.

Inhaled nitric oxide for adults with pulmonary nontuberculous mycobacterial infection. Respir Med. 2023 01; 206:107069.

The expression of pregnancyassociated plasma proteinA (PAPPA) in human blastocoel fluidconditioned media: a proof of concept study. J Assist Reprod Genet. 2022 Feb; 39(2):389394.

Diabetes Patient Surveillance in the Emergency Department: Proof of Concept and Opportunities. West J Emerg Med. 2021 Apr 02; 22(3):636643.

Extracellular matrix alterations in lowgrade lung adenocarcinoma compared with normal lung tissue by imaging mass spectrometry. J Mass Spectrom. 2020 Apr; 55(4):e4450.

18FAzaFol for Detection of Folate Receptor? Positive Macrophages in Experimental Interstitial Lung DiseaseA ProofofConcept Study. Front Immunol. 2019; 10:2724.

Sorafenib in Hepatopulmonary Syndrome: A Randomized, DoubleBlind, PlaceboControlled Trial. Liver Transpl. 2019 08; 25(8):11551164.

Visualisation of interstitial lung disease by molecular imaging of integrin av?3 and somatostatin receptor 2. Ann Rheum Dis. 2019 02; 78(2):218227.

Low CT temporal sampling rates result in a substantial underestimation of myocardial blood flow measurements. Int J Cardiovasc Imaging. 2019 Mar; 35(3):539547.

Identification of Phenotypic Patterns of Dysphagia: A Proof of Concept Study. Am J Speech Lang Pathol. 2018 08 06; 27(3):988995.

A multisite proofofconcept investigation of computerized approachavoidance training in adolescent cannabis users. Drug Alcohol Depend. 2018 06 01; 187:195204.