"Zinc Finger Protein Gli2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.
Below are MeSH descriptors whose meaning is more general than "Zinc Finger Protein Gli2".
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Below are the most recent publications written about "Zinc Finger Protein Gli2" by people in Profiles.
TAK1/Map3k7 enhances differentiation of cardiogenic endoderm from mouse embryonic stem cells. J Mol Cell Cardiol. 2019 12; 137:132-142.
Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis. J Biol Chem. 2016 Dec 02; 291(49):25749-25760.
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. Genes Dev. 2016 09 01; 30(17):1943-55.
Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol. 2014 Dec 15; 281(3):243-53.