"Drug Inverse Agonism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phenomena and pharmaceutics of compounds that bind to the same receptor binding-site as an agonist (DRUG AGONISM) for that receptor but exerts the opposite pharmacological effect.
| Descriptor ID |
D054314
|
| MeSH Number(s) |
G07.690.773.968.393
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Drug Inverse Agonism".
Below are MeSH descriptors whose meaning is more specific than "Drug Inverse Agonism".
This graph shows the total number of publications written about "Drug Inverse Agonism" by people in this website by year, and whether "Drug Inverse Agonism" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Drug Inverse Agonism" by people in Profiles.
-
Pandey P, Roy KK, Liu H, Ma G, Pettaway S, Alsharif WF, Gadepalli RS, Rimoldi JM, McCurdy CR, Cutler SJ, Doerksen RJ. Structure-Based Identification of Potent Natural Product Chemotypes as Cannabinoid Receptor 1 Inverse Agonists. Molecules. 2018 Oct 13; 23(10).
-
Pava MJ, Makriyannis A, Lovinger DM. Endocannabinoid Signaling Regulates Sleep Stability. PLoS One. 2016; 11(3):e0152473.
-
Kono M, Crouch RK. In vitro assays of rod and cone opsin activity: retinoid analogs as agonists and inverse agonists. Methods Mol Biol. 2010; 652:85-94.
-
Kono M. Assays for inverse agonists in the visual system. Methods Enzymol. 2010; 485:213-24.
-
Ala-Laurila P, Cornwall MC, Crouch RK, Kono M. The action of 11-cis-retinol on cone opsins and intact cone photoreceptors. J Biol Chem. 2009 Jun 12; 284(24):16492-16500.