"Hydroxycholesterols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cholesterol which is substituted by a hydroxy group in any position.
Below are MeSH descriptors whose meaning is more general than "Hydroxycholesterols".
Below are MeSH descriptors whose meaning is more specific than "Hydroxycholesterols".
This graph shows the total number of publications written about "Hydroxycholesterols" by people in this website by year, and whether "Hydroxycholesterols" was a major or minor topic of these publications.
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Below are the most recent publications written about "Hydroxycholesterols" by people in Profiles.
Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B. Differential expression of cholesterol hydroxylases in Alzheimer's disease. J Biol Chem. 2004 Aug 13; 279(33):34674-81.
Peffley DM, Gayen AK. Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level. Arch Biochem Biophys. 1997 Jan 15; 337(2):251-60.
Gayen AK, Peffley DM. The length of 5'-untranslated leader sequences influences distribution of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in polysomes: effects of lovastatin, oxysterols, and mevalonate. Arch Biochem Biophys. 1995 Oct 01; 322(2):475-85.
Peffley DM, Gayen AK. Mevalonate regulates polysome distribution and blocks translation-dependent suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA: relationship to translational control. Somat Cell Mol Genet. 1995 May; 21(3):189-204.
Choi JW, Peffley DM. 3'-untranslated sequences mediate post-transcriptional regulation of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA by 25-hydroxycholesterol. Biochem J. 1995 Apr 01; 307 ( Pt 1):233-8.
Choi JW, Lundquist EN, Peffley DM. Inhibition of protein synthesis in baby-hamster kidney cells blocks oxysterol-mediated suppression of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA at a post-transcriptional level. Biochem J. 1993 Dec 15; 296 ( Pt 3):859-66.
Peffley DM. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis in Syrian hamster C100 cells by mevinolin, 25-hydroxycholesterol, and mevalonate: the role of posttranscriptional control. Somat Cell Mol Genet. 1992 Jan; 18(1):19-32.
Boissonneault GA, Hennig B, Ouyang CM. Oxysterols, cholesterol biosynthesis, and vascular endothelial cell monolayer barrier function. Proc Soc Exp Biol Med. 1991 Mar; 196(3):338-43.
Peffley D, Miyake J, Leonard S, von Gunten C, Sinensky M. Further characterization of a somatic cell mutant defective in regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Somat Cell Mol Genet. 1988 Nov; 14(6):527-39.
Peffley D, Sinensky M. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis by a non-sterol mevalonate-derived product in Mev-1 cells. Apparent translational control. J Biol Chem. 1985 Aug 25; 260(18):9949-52.