"Integrases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.
| Descriptor ID |
D019426
|
| MeSH Number(s) |
D08.811.739.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Integrases".
Below are MeSH descriptors whose meaning is more specific than "Integrases".
This graph shows the total number of publications written about "Integrases" by people in this website by year, and whether "Integrases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 2 | 3 |
| 2002 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrases" by people in Profiles.
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Impact of Integrase Strand Transfer Inhibitor Use During Pregnancy on Viral Suppression at Delivery and Infant Outcomes: A Statewide Retrospective Cohort Study. J Acquir Immune Defic Syndr. 2022 04 01; 89(4):448-453.
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Prototype Foamy Virus Integrase Displays Unique Biochemical Activities among Retroviral Integrases. Biomolecules. 2021 12 20; 11(12).
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The paraventricular thalamus provides a polysynaptic brake on limbic CRF neurons to sex-dependently blunt binge alcohol drinking and avoidance behavior in mice. Nat Commun. 2021 08 23; 12(1):5080.
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The Use of Integrase Strand Transfer Inhibitors to Treat HIV in Pregnancy. J Midwifery Womens Health. 2021 May; 66(3):403-406.
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Cre-dependent AAV vectors for highly targeted expression of disease-related proteins and neurodegeneration in the substantia nigra. FASEB J. 2018 08; 32(8):4420-4427.
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Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing. Mol Neurobiol. 2018 Aug; 55(8):6518-6532.
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Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development. Development. 2015 Jun 01; 142(11):2037-47.
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Hyperactive transforming growth factor-?1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model. J Bone Miner Res. 2013 Dec; 28(12):2476-89.
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Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. Mech Dev. 2013 Apr-May; 130(4-5):272-89.
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Atypical E2F repressors and activators coordinate placental development. Dev Cell. 2012 Apr 17; 22(4):849-62.