"Receptors, Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in signaling a variety of immunological responses related to allergic INFLAMMATION including the differentiation of TH2 CELLS and the regulation of IMMUNOGLOBULIN E production. Two subtypes of receptors exist and are referred to as the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEUKIN-4 RECEPTOR. Each receptor subtype is defined by its unique subunit composition.
Descriptor ID |
D019948
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MeSH Number(s) |
D12.776.543.750.705.852.420.360
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Concept/Terms |
Receptors, Interleukin-4- Receptors, Interleukin-4
- Receptors, Interleukin 4
- IL-4 Receptors
- IL 4 Receptors
- Receptors, IL-4
- Receptors, IL 4
- IL4 Receptors
- Receptors, IL4
- Interleukin 4 Receptor
- Receptor, Interleukin 4
- Interleukin-4 Receptors
- Interleukin 4 Receptors
- IL-4 Receptor
- IL 4 Receptor
- Receptor, IL-4
- IL4 Receptor
- Receptor, IL4
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-4".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-4".
This graph shows the total number of publications written about "Receptors, Interleukin-4" by people in this website by year, and whether "Receptors, Interleukin-4" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2010 | 1 | 1 | 2 |
2011 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Interleukin-4" by people in Profiles.
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Signaling through the interleukin-4 and interleukin-13 receptor complexes regulates cholangiocyte TMEM16A expression and biliary secretion. Am J Physiol Gastrointest Liver Physiol. 2020 04 01; 318(4):G763-G771.
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Impact of single nucleotide polymorphism in IL-4, IL-4R genes and systemic concentration of IL-4 on the incidence of glioma in Iraqi patients. Int J Med Sci. 2014; 11(11):1147-53.
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IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma. Clin Cancer Res. 2011 May 01; 17(9):2757-66.
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Association of IL4R single-nucleotide polymorphisms with rheumatoid nodules in African Americans with rheumatoid arthritis. Arthritis Res Ther. 2010; 12(3):R75.
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IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis. J Immunol. 2010 May 01; 184(9):4688-95.
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Neutralizing endogenous IL-6 renders mast cells of the MCT type from lung, but not the MCTC type from skin and lung, susceptible to human recombinant IL-4-induced apoptosis. J Immunol. 2004 Jan 01; 172(1):593-600.
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Recombinant human (rh)IL-4-mediated apoptosis and recombinant human IL-6-mediated protection of recombinant human stem cell factor-dependent human mast cells derived from cord blood mononuclear cell progenitors. J Immunol. 1999 Nov 01; 163(9):5105-15.
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Evidence for the participation of interleukin-2 (IL-2) and IL-4 in the regulation of autonomous growth and tumorigenesis of transformed cells of lymphoid origin. Blood. 1997 Jan 15; 89(2):610-20.