"Angiotensin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A decapeptide that is cleaved from precursor angiotensinogen by RENIN. Angiotensin I has limited biological activity. It is converted to angiotensin II, a potent vasoconstrictor, after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME.
Descriptor ID |
D000803
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MeSH Number(s) |
D06.472.699.094.075 D12.644.400.070.075 D12.644.456.073.021 D12.644.548.058.075 D12.776.631.650.070.075 D23.469.050.050.025
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Angiotensin I".
Below are MeSH descriptors whose meaning is more specific than "Angiotensin I".
This graph shows the total number of publications written about "Angiotensin I" by people in this website by year, and whether "Angiotensin I" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 2 | 2 |
2003 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Angiotensin I" by people in Profiles.
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Egan BM, Laken MA, Sutherland SE, Qanungo S, Fleming DO, Cook AG, Hester WH, Jones KW, Jebaily GC, Valainis GT, Way CF, Wright MB, Davis RA. Aldosterone Antagonists or Renin-Guided Therapy for Treatment-Resistant Hypertension: A Comparative Effectiveness Pilot Study in Primary Care. Am J Hypertens. 2016 08; 29(8):976-83.
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Velez JC, Janech MG, Hicks MP, Morinelli TA, Rodgers J, Self SE, Arthur JM, Fitzgibbon WR. Lack of renoprotective effect of chronic intravenous angiotensin-(1-7) or angiotensin-(2-10) in a rat model of focal segmental glomerulosclerosis. PLoS One. 2014; 9(10):e110083.
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Velez JC, Ierardi JL, Bland AM, Morinelli TA, Arthur JM, Raymond JR, Janech MG. Enzymatic processing of angiotensin peptides by human glomerular endothelial cells. Am J Physiol Renal Physiol. 2012 Jun 15; 302(12):F1583-94.
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Velez JC, Ryan KJ, Harbeson CE, Bland AM, Budisavljevic MN, Arthur JM, Fitzgibbon WR, Raymond JR, Janech MG. Angiotensin I is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli. Hypertension. 2009 May; 53(5):790-7.
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Velez JC, Bland AM, Arthur JM, Raymond JR, Janech MG. Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F398-407.
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Flesch M, Höper A, Dell'Italia L, Evans K, Bond R, Peshock R, Diwan A, Brinsa TA, Wei CC, Sivasubramanian N, Spinale FG, Mann DL. Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor. Circulation. 2003 Aug 05; 108(5):598-604.
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Perry GJ, Wei CC, Hankes GH, Dillon SR, Rynders P, Mukherjee R, Spinale FG, Dell'Italia LJ. Angiotensin II receptor blockade does not improve left ventricular function and remodeling in subacute mitral regurgitation in the dog. J Am Coll Cardiol. 2002 Apr 17; 39(8):1374-9.
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Wei CC, Ferrario CM, Brosnihan KB, Farrell DM, Bradley WE, Jaffa AA, Dell'Italia LJ. Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo. J Pharmacol Exp Ther. 2002 Jan; 300(1):324-9.
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Kim JS, Knapp DR. Miniaturized multichannel electrospray ionization emitters on poly(dimethylsiloxane) microfluidic devices. Electrophoresis. 2001 Oct; 22(18):3993-9.
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Busman M, Knapp DR, Schey KL. Observation of large multimers in the electrospray ionization mass spectrometry of peptides. Rapid Commun Mass Spectrom. 1994 Feb; 8(2):211-6.