"Hexamethonium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Descriptor ID |
D018738
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MeSH Number(s) |
D02.092.877.250.592.400 D02.675.276.558.592.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hexamethonium".
Below are MeSH descriptors whose meaning is more specific than "Hexamethonium".
This graph shows the total number of publications written about "Hexamethonium" by people in this website by year, and whether "Hexamethonium" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 2 | 2 |
2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hexamethonium" by people in Profiles.
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Endogenous ouabain-like factor (OLF) secretion is modulated by nicotinic mechanisms in rat adrenocortical cells. Life Sci. 2004 Mar 12; 74(17):2111-28.
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Guinea pig pancreatic neurons: morphology, neurochemistry, electrical properties, and response to 5-HT. Am J Physiol. 1997 12; 273(6):G1273-89.
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Glutamatergic enteric neurons. J Neurosci. 1997 Jun 15; 17(12):4764-84.