"Cataplexy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition characterized by transient weakness or paralysis of somatic musculature triggered by an emotional stimulus or physical exertion. Cataplexy is frequently associated with NARCOLEPSY. During a cataplectic attack, there is a marked reduction in muscle tone similar to the normal physiologic hypotonia that accompanies rapid eye movement sleep (SLEEP, REM). (From Adams et al., Principles of Neurology, 6th ed, p396)
| Descriptor ID |
D002385
|
| MeSH Number(s) |
C10.886.425.800.200.750.500 F03.870.400.800.200.750.500
|
| Concept/Terms |
Cataplexy- Cataplexy
- Tonelessness Syndrome
- Syndrome, Tonelessness
- Syndromes, Tonelessness
- Tonelessness Syndromes
- Cataleptic Attacks
- Attack, Cataleptic
- Attacks, Cataleptic
- Cataleptic Attack
- Henneberg Syndrome
- Syndrome, Henneberg
|
Below are MeSH descriptors whose meaning is more general than "Cataplexy".
Below are MeSH descriptors whose meaning is more specific than "Cataplexy".
This graph shows the total number of publications written about "Cataplexy" by people in this website by year, and whether "Cataplexy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cataplexy" by people in Profiles.
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Changes in Cataplexy Frequency in a Clinical Trial of Lower-Sodium Oxybate with Taper and Discontinuation of Other Anticataplectic Medications. CNS Drugs. 2022 06; 36(6):633-647.
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Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate [LXB]; JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy. Sleep. 2021 03 12; 44(3).
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The a6 GABAA Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome. Biomolecules. 2021 01 28; 11(2).
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Update on the pharmacologic management of narcolepsy: mechanisms of action and clinical implications. Sleep Med. 2020 04; 68:97-109.
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Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy. Elife. 2019 08 14; 8.
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Longitudinal study of narcolepsy symptoms in first, second, and third-degree relatives of simplex and multiplex narcolepsy families. Sleep Med. 2019 01; 53:88-93.
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Rewiring brain circuits to block cataplexy in murine models of narcolepsy. Curr Opin Neurobiol. 2017 06; 44:110-115.
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Impact of sodium oxybate, modafinil, and combination treatment on excessive daytime sleepiness in patients who have narcolepsy with or without cataplexy. Sleep Med. 2016 08; 24:57-62.
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Orexin gene transfer into the amygdala suppresses both spontaneous and emotion-induced cataplexy in orexin-knockout mice. Eur J Neurosci. 2016 Mar; 43(5):681-8.
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Effects of orexin gene transfer in the dorsolateral pons in orexin knockout mice. Sleep. 2013 Jan 01; 36(1):31-40.