"Polyadenylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The addition of a tail of polyadenylic acid (POLY A) to the 3' end of mRNA (RNA, MESSENGER). Polyadenylation involves recognizing the processing site signal, (AAUAAA), and cleaving of the mRNA to create a 3' OH terminal end to which poly A polymerase (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) adds 60-200 adenylate residues. The 3' end processing of some messenger RNAs, such as histone mRNA, is carried out by a different process that does not include the addition of poly A as described here.
Below are MeSH descriptors whose meaning is more general than "Polyadenylation".
Below are MeSH descriptors whose meaning is more specific than "Polyadenylation".
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Below are the most recent publications written about "Polyadenylation" by people in Profiles.
Barrows JK, Long DT. Cell-free transcription in Xenopus egg extract. J Biol Chem. 2019 12 20; 294(51):19645-19654.
Palaniswamy V, Moraes KC, Wilusz CJ, Wilusz J. Nucleophosmin is selectively deposited on mRNA during polyadenylation. Nat Struct Mol Biol. 2006 May; 13(5):429-35.