"DNA Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
Descriptor ID |
D004260
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MeSH Number(s) |
G02.111.222 G05.219
|
Concept/Terms |
Base Excision Repair- Base Excision Repair
- Base Excision Repairs
- Excision Repair, Base
- Repair, Base Excision
- Repairs, Base Excision
|
Below are MeSH descriptors whose meaning is more general than "DNA Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Repair".
This graph shows the total number of publications written about "DNA Repair" by people in this website by year, and whether "DNA Repair" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 2 | 2 |
1997 | 1 | 0 | 1 |
1998 | 1 | 1 | 2 |
2000 | 1 | 2 | 3 |
2001 | 2 | 0 | 2 |
2002 | 0 | 2 | 2 |
2003 | 4 | 2 | 6 |
2004 | 3 | 3 | 6 |
2005 | 6 | 1 | 7 |
2006 | 6 | 1 | 7 |
2007 | 4 | 2 | 6 |
2008 | 2 | 1 | 3 |
2009 | 3 | 2 | 5 |
2010 | 3 | 3 | 6 |
2011 | 2 | 2 | 4 |
2012 | 3 | 4 | 7 |
2013 | 2 | 1 | 3 |
2014 | 4 | 4 | 8 |
2015 | 5 | 1 | 6 |
2016 | 5 | 1 | 6 |
2017 | 1 | 0 | 1 |
2018 | 3 | 0 | 3 |
2019 | 4 | 0 | 4 |
2020 | 1 | 1 | 2 |
2021 | 1 | 1 | 2 |
2022 | 1 | 3 | 4 |
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Below are the most recent publications written about "DNA Repair" by people in Profiles.
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Redox regulation of RAD51 Cys319 and homologous recombination by peroxiredoxin 1. Redox Biol. 2022 10; 56:102443.
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UV Irradiation of Vaccinia Virus-Infected Cells Impairs Cellular Functions, Introduces Lesions into the Viral Genome, and Uncovers Repair Capabilities for the Viral Replication Machinery. J Virol. 2022 05 11; 96(9):e0213721.
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miRNA and lncRNA Expression Networks Modulate Cell Cycle and DNA Repair Inhibition in Senescent Prostate Cells. Genes (Basel). 2022 01 24; 13(2).
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Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency. Nat Med. 2022 01; 28(1):125-135.
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Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair. Free Radic Biol Med. 2021 06; 169:238-247.
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Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2021 05; 30(5):895-903.
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Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break. Nat Commun. 2020 11 13; 11(1):5776.
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Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns. Acta Neuropathol. 2020 11; 140(5):765-776.
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DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility. Int J Cancer. 2020 01 15; 146(2):363-372.
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Homologous recombination and DNA repair mutations in patients treated with carboplatin and nab-paclitaxel for metastatic non-small cell lung cancer. Lung Cancer. 2019 08; 134:167-173.