"Complement C2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
| Descriptor ID |
D003175
|
| MeSH Number(s) |
D12.776.124.486.274.150
|
| Concept/Terms |
Complement C2- Complement C2
- C2, Complement
- Complement 2
- Complement Component 2
- Component 2, Complement
- C2 Complement
- Complement, C2
|
Below are MeSH descriptors whose meaning is more general than "Complement C2".
Below are MeSH descriptors whose meaning is more specific than "Complement C2".
This graph shows the total number of publications written about "Complement C2" by people in this website by year, and whether "Complement C2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Complement C2" by people in Profiles.
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Chronic complement dysregulation drives neuroinflammation after traumatic brain injury: a transcriptomic study. Acta Neuropathol Commun. 2021 07 19; 9(1):126.
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Increasing the efficacy and safety of a human complement inhibitor for treating post-transplant cardiac ischemia reperfusion injury by targeting to a graft-specific neoepitope. J Heart Lung Transplant. 2021 10; 40(10):1112-1121.
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Does C-2 kinin exist? J Allergy Clin Immunol. 2005 Apr; 115(4):876.
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Synthesis of C1 inhibitor (C1-INA) by a human monocyte-like cell line, U937. J Immunol. 1985 Aug; 135(2):1313-9.
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Kinin formation in hereditary angioedema plasma: evidence against kinin derivation from C2 and in support of "spontaneous" formation of bradykinin. J Allergy Clin Immunol. 1983 Jul; 72(1):54-60.
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Activation of the classical pathway of complement by Hageman factor fragment. J Exp Med. 1981 Mar 01; 153(3):665-76.