"CD4 Immunoadhesins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.
Below are MeSH descriptors whose meaning is more general than "CD4 Immunoadhesins".
Below are MeSH descriptors whose meaning is more specific than "CD4 Immunoadhesins".
This graph shows the total number of publications written about "CD4 Immunoadhesins" by people in this website by year, and whether "CD4 Immunoadhesins" was a major or minor topic of these publications.
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Below are the most recent publications written about "CD4 Immunoadhesins" by people in Profiles.
Rathore YS, Solanki AK, Dhoke RR. SAXS data analysis and modeling of tetravalent neutralizing antibody CD4-IgG2 -/+ HIV-1 gp120 revealed that first two gp120 bind to the same Fab arm. Biochem Biophys Res Commun. 2011 Dec 02; 415(4):680-5.
Pule M, Finney H, Lawson A. Artificial T-cell receptors. Cytotherapy. 2003; 5(3):211-26.