Epithelial Cell Adhesion Molecule
"Epithelial Cell Adhesion Molecule" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.
| Descriptor ID |
D000071858
|
| MeSH Number(s) |
D12.776.395.550.200.263 D12.776.543.550.200.263 D23.050.285.357 D23.050.301.350.263
|
| Concept/Terms |
Epithelial Cell Adhesion Molecule- Epithelial Cell Adhesion Molecule
- CD326 Protein
- Antigen, CD326
- CD326 Antigen
- ESA Antigen
- Antigen, ESA
- EpCAM
- GA733 Antigen
- Antigen, GA733
- GA733 Tumor-Associated Antigen
- GA733 Tumor Associated Antigen
- Tumor-Associated Antigen, GA733
- Tacstd1 Protein
- Epithelial Specific Antigen
- Antigen, Epithelial Specific
- Ep-CAM
- Tumor-Associated Antigen GA733
- GA733, Tumor-Associated Antigen
- Tumor Associated Antigen GA733
- GA 733 Tumor-Associated Antigen
- GA 733 Tumor Associated Antigen
|
Below are MeSH descriptors whose meaning is more general than "Epithelial Cell Adhesion Molecule".
Below are MeSH descriptors whose meaning is more specific than "Epithelial Cell Adhesion Molecule".
This graph shows the total number of publications written about "Epithelial Cell Adhesion Molecule" by people in this website by year, and whether "Epithelial Cell Adhesion Molecule" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Epithelial Cell Adhesion Molecule" by people in Profiles.
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Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome. Br J Cancer. 2019 11; 121(10):869-876.
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Childhood cancers in families with and without Lynch syndrome. Fam Cancer. 2015 Dec; 14(4):545-51.
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Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer. Mol Cancer Ther. 2012 Nov; 11(11):2526-34.
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Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-?1-dependent human epidermal Langerhans cells. J Invest Dermatol. 2011 Oct; 131(10):2049-57.
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Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases. J Mol Diagn. 2011 Jan; 13(1):93-9.
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Detection of circulating tumor cells in the peripheral blood of patients with androgen-independent, advanced or metastatic prostate cancer. Am J Hematol. 2008 Jan; 83(1):87.
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Accurate discrimination of pancreatic ductal adenocarcinoma and chronic pancreatitis using multimarker expression data and samples obtained by minimally invasive fine needle aspiration. Int J Cancer. 2007 Apr 01; 120(7):1511-7.
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EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy. Cancer Res. 2004 Aug 15; 64(16):5818-24.
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Cancer-associated molecular signature in the tissue samples of patients with cirrhosis. Hepatology. 2004 Feb; 39(2):518-27.