"Leukotriene C4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
| Descriptor ID |
D017997
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| MeSH Number(s) |
D10.251.355.255.100.450.855.455 D10.251.355.310.166.887.855.455 D23.469.050.175.450.725.400
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Leukotriene C4".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene C4".
This graph shows the total number of publications written about "Leukotriene C4" by people in this website by year, and whether "Leukotriene C4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukotriene C4" by people in Profiles.
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Surface CD88 functionally distinguishes the MCTC from the MCT type of human lung mast cell. J Allergy Clin Immunol. 2005 Jun; 115(6):1162-8.
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Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug. Mol Pharmacol. 2004 May; 65(5):1070-9.
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Arachidonic acid and leukotriene C4: role in transient cerebral ischemia of gerbils. Neurochem Res. 1999 Oct; 24(10):1225-32.
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Excretory transport of xenobiotics by dogfish shark rectal gland tubules. Am J Physiol. 1998 09; 275(3):R697-705.
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ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter. Proc Natl Acad Sci U S A. 1996 Jul 09; 93(14):6929-34.