"Serotonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
| Descriptor ID |
D012701
|
| MeSH Number(s) |
D02.092.211.215.801.852 D03.633.100.473.914.814 D23.469.050.650
|
| Concept/Terms |
Serotonin- Serotonin
- 5-Hydroxytryptamine
- 5 Hydroxytryptamine
- Hippophaine
- 3-(2-Aminoethyl)-1H-indol-5-ol
- Enteramine
- 5-HT
|
Below are MeSH descriptors whose meaning is more general than "Serotonin".
Below are MeSH descriptors whose meaning is more specific than "Serotonin".
This graph shows the total number of publications written about "Serotonin" by people in this website by year, and whether "Serotonin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 4 | 5 |
| 1995 | 1 | 5 | 6 |
| 1996 | 2 | 2 | 4 |
| 1997 | 1 | 1 | 2 |
| 1998 | 3 | 2 | 5 |
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 1 | 2 |
| 2003 | 1 | 4 | 5 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 5 | 6 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 3 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 2 | 1 | 3 |
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Below are the most recent publications written about "Serotonin" by people in Profiles.
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Targeting 5-HT2A receptors and Kv7 channels in PFC to attenuate chronic neuropathic pain in rats using a spared nerve injury model. Neurosci Lett. 2022 10 15; 789:136864.
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A tale of two transmitters: serotonin and histamine as in vivo biomarkers of chronic stress in mice. J Neuroinflammation. 2022 Jun 27; 19(1):167.
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EGD for Refractory Toxidromes: Is It Time to Add to the Algorithm? J Investig Med High Impact Case Rep. 2022 Jan-Dec; 10:23247096221106760.
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Inflammation-Induced Histamine Impairs the Capacity of Escitalopram to Increase Hippocampal Extracellular Serotonin. J Neurosci. 2021 07 28; 41(30):6564-6577.
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Plant-Based Nutritional Supplementation Attenuates LPS-Induced Low-Grade Systemic Activation. Int J Mol Sci. 2021 Jan 08; 22(2).
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Histamine Receptors Regulate the Activity, Surface Expression, and Phosphorylation of Serotonin Transporters. ACS Chem Neurosci. 2020 02 05; 11(3):466-476.
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Modulation of serotonin transporter function by kappa-opioid receptor ligands. Neuropharmacology. 2017 02; 113(Pt A):281-292.
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Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis. J Neuroimmune Pharmacol. 2016 12; 11(4):763-773.
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Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC a-synuclein transgenic rat model of Parkinson's disease. Neurobiol Dis. 2016 Jan; 85:206-217.
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Akt-mediated regulation of antidepressant-sensitive serotonin transporter function, cell-surface expression and phosphorylation. Biochem J. 2015 May 15; 468(1):177-90.